Bravecto PLUS Topical for Cats (8 Weeks)

BRAVECTO PLUS (fluralaner and moxidectin topical solution) for Cats offers protection against fleas, ticks, and heartworms for 2 months*, and treats and controls roundworms and hookworms. This vet-recommended and FDA-approved topical solution for cats is the first U.S. product that provides protection against the Asian longhorned tick.

*BRAVECTO PLUS is indicated for the prevention of heartworm disease caused by Dirofilaria immitis and for the treatment of infections with intestinal roundworm (Toxocara cati; 4th stage larvae, immature adults and adults) and hookworm (Ancylostoma tubaeforme; 4th stage larvae, immature adults and adults). BRAVECTO PLUS kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and the treatment and control of tick infestations [Ixodes scapularis (black-legged tick) and Dermacentor variabilis (American dog tick) and Haemaphysalis longicornis (Asian longhorned tick)] for 2 months in cats and kittens 6 months of age and older and weighing 2.6 lbs or greater.

Cats and Kittens (6 months of age and older)

Fluralaner, Moxidectin

Dimethylacetamide, glycofurol, diethyltoluamide, acetone, butylhydroxytoluene.

BRAVECTO PLUS Topical Solution for Cats

Isoxazoline ectoparasiticide, Macrocyclic lactone antiparasitic, Topical

Merck Animal Health

Weight band	Weight Range	Fluralaner content	Moxidectin content
Small cats	2.6 to 6.2 lbs	112.5 mg	5.6 mg
Medium-sized cats	>6.2 to 13.8 lbs	250 mg	12.5 mg
Large cats	>13.8 to 27.5* lbs	500 mg	25 mg

*For cats over 27.5 lbs, administer the appropriate combination of tubes to cover your cat’s body weight.

BRAVECTO PLUS Topical Solution for Cats should be applied topically as directed by your veterinarian.

Manufacturer Dosage and Administration:

Bravecto Plus Topical Solution should be administered topically as a single dose every 2 months according to your cat’s body weight to provide a minimum dose of 18.2 mg/lb (40 mg/kg) fluralaner and 0.9 mg/lb (2 mg/kg) moxidectin.

For prevention of heartworm disease, Bravecto Plus should be administered at 2-month intervals. Bravecto Plus may be administered year-round without interruption or at a minimum should be administered at 2-month intervals beginning at the cat's first seasonal exposure to mosquitoes and continuing until the cat's last seasonal exposure to mosquitoes. If a dose is missed and a 2-month interval between doses is exceeded, administer Bravecto Plus immediately and resume the dosing every 2 months.

When replacing a monthly heartworm preventative product, the first dose of Bravecto Plus should be given within one month of the last dose of the former medication.

A veterinarian or veterinary technician should demonstrate or instruct the pet owner regarding the appropriate technique for applying Bravecto Plus topically to cats prior to first use.

Step 1: Immediately before use, open the pouch and remove the tube. Put on gloves. Hold the tube at the crimped end with the cap in an upright position (tip up). The cap should be rotated clockwise or counterclockwise one full turn. The cap is designed to stay on the tube for dosing and should not be removed. The tube is open and ready for application when a breaking of the seal is felt.

Step 2: The cat should be standing or lying with its back horizontal during application. Part the fur at the administration site. Place the tube tip vertically against the skin at the base of the skull of the cat.

Step 3: Squeeze the tube and gently apply the entire contents of Bravecto Plus directly to the skin at the base of the skull of the cat. Avoid applying an excessive amount of solution that could cause some of the solution to run and drip off of the cat. If a second spot is needed to avoid runoff, apply the second spot slightly behind the first spot.

Greasy, oily, or wet appearance may occur at the application site in some cats.

If a dose is missed: apply BRAVECTO PLUS Topical Solution as soon as you remember, then wait for the full prescribed dosing interval prior to administering the next dose. Do not apply two doses at once.

If you have questions about your pet’s prescribed dosing schedule (e.g., timing, interval), please consult your veterinarian.

Store in a cool, dry place at a controlled room temperature (at or below 77°F). Keep out of the reach of children and pets. The medication should remain sealed in its original packaging to protect from moisture. The pouch should only be opened immediately prior to use. Store away from heat and direct sunlight.

Do not store in the bathroom, near the kitchen sink, or in damp places. The medicine may break down if exposed to heat or moisture.

BRAVECTO PLUS Topical Solution is generally well tolerated. The most common side effects of this medication are application site reactions (e.g., hair loss, redness, dry skin, itching), generalized itching or hair loss (not at the application site), vomiting, diarrhea, decreased appetite, itching, hypersalivation (drooling), and drowsiness/lethargy.

Contact your veterinarian immediately if your pet experiences severe or persistent vomiting, complete loss of appetite, has a seizure or any other neurologic adverse reaction (e.g., tremors, loss of coordination, weakness), or if you notice swelling of the chin, lips, or the area around the eyes.

Notify your veterinarian if your pet experiences any of the effects described above, or if you notice any other side effects that are persistent or troublesome.

If you notice anything unusual, please consult your veterinarian.

For topical use on cats only- avoid oral ingestion. Not for human use. Keep this and all drugs out of the reach of children.

Do not contact or allow children to contact the application site until 2 hours post-application.

Keep the product in the original packaging until use to prevent children from getting direct access to the product. Do not eat, drink, or smoke while handling the product. Avoid contact with skin and eyes. If contact with eyes occurs, flush eyes slowly and gently with water. If wearing contact lenses, eyes should be rinsed first, then remove contact lenses and continue rinsing, then seek medical advice immediately. Wash hands and contacted skin thoroughly with soap and water immediately after use of the product. If the product accidentally contacts skin and a sticky residue persists after washing, rubbing alcohol (70% isopropyl alcohol) can be applied to the area to remove the residue.

This product is highly flammable. Keep away from heat, sparks, open flame, or other sources of ignition.

Fluralaner, one of the ingredients in Bravecto Plus, is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Neurologic adverse reactions have been reported in cats receiving isoxazoline class drugs, even in cats without a history of neurologic disorders. Use with caution in cats with a history of neurologic disorders.

Use with caution in cats that are heartworm positive.

Bravecto Plus has not been shown to be effective in kittens less than 6 months of age.

The safety of Bravecto Plus has not been established in breeding, pregnant, and lactating cats. Discuss the risks of using this medication with your veterinarian if your pet is in one of these groups.

The effectiveness of Bravecto Plus to prevent heartworm disease after bathing or water immersion has not been evaluated.

Do not administer to animals with a known history or suspected allergy/hypersensitivity to any isoxazoline class drug, including this medication or any of its ingredients. Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies.

If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways; difficulty breathing; agitation; profuse salivation; and widespread hives or itching.

There are no documented drug or food interactions with this medication.

Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.

Please ensure your veterinarian is aware of all medications and supplements that your pet is currently receiving. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.

If you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer Merck Animal Health at 1-800-224-5318 or Vetsource Pet Owner Care at 877-738-4443.

If you have any reason to suspect an overdose, call your doctor/veterinarian or the appropriate poison control resource immediately.

For humans:

The national toll-free Poison Help line, 1-800-222-1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories.

For animals:

The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888-426-4435.

Pet Poison Helpline® also provides a 24/7 animal poison control service at 855-764-7661.

All content, including the images and product description above, is intended for general informational purposes only and should not be considered a substitute for professional veterinary consultation, diagnosis, or treatment.

Consult your veterinarian for complete information about this product and how it fits into your pet's individual treatment plan.