Product Information

Description

Product details

Credelio CAT (lotilaner) is the first flea and tick chewable tablet for cats, administered once per month to kill adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) in cats and kittens 8 weeks of age and older, and weighing 2 pounds or greater. CREDELIO CAT is also indicated for the treatment and control of Ixodes scapularis (black-legged tick) infestations for one month in cats and kittens 6 months of age and older, and weighing 2 pounds or greater.

The first flea and tick infestation prevention and treatment chewable tablet for cats & kittens 8+ weeks of age, and weighing 2 pounds or greater
Fast-acting ingredients start killing adult fleas in just 6 hours
Small, tasty chewable tablet made with vanilla & yeast to appeal to cats
Works hard all month long
Easy to give; Credelio CAT was successfully given by over 99% of cat owners (Chappell K, Paarlberg T, Seewald W, et al. A randomized, controlled field study to assess the efficacy and safety of lotilaner flavored chewable tablets (Credelio® CAT) in eliminating fleas in client-owned cats in the USA. Parasite Vector. 2021;14:127.)

Product sourced directly from the manufacturer or their approved distributor. Guaranteed genuine product backed by the manufacturer.

For

Cats (8 weeks of age and older)

Active ingredient(s)

Lotilaner

Inactive ingredients

Complete inactive ingredients list not provided by manufacturer.

Brand name

Credelio CAT

Drug class

Isoxazoline ectoparasiticide

Product flavoring

Credelio CAT is vanilla yeast flavored.

*Contains vanilla, yeast

Manufacturer

Elanco

Product strength & size

Weight range	Lotilaner (per chewable tablet)	Chewable tablets administered
2 to 4 lbs	12 mg	One
4.1 to 17* lbs	48 mg	One

*For cats over 17 lbs, administer the appropriate combination of chewable tablets to cover your pet’s body weight.

Usage

*For complete product information, please review the full prescribing information in the manufacturer package insert.

Manufacturer Dosage and Administration:

CREDELIO CAT is given orally once a month, at the minimum dosage of 2.7 mg/lb (6 mg/kg).

All owners have different comfort levels with their cat when it comes to administering medication. There are three basic ways to administer Credelio Cat:

1) Offer by hand or place in area where your cat feels comfortable eating. Many cats will eat the chewable by free choice. Tempting with treats can also help.

2) Offer with food during a meal. If your cat is a grazer, try placing it around a few pieces of kibble or covered in wet food and checking to make sure it has been consumed out of the bowl.

3) Place the chewable on the back of your cat’s tongue. The chewables were designed to be very small and easy to administer in these situations. It is important to always administer Credelio Cat with a meal or 30 minutes after feeding.

Treatment with CREDELIO CAT can begin at any time of the year and can continue year-round without interruption.

Missed doses

Treatment should be administered monthly. If a dose is missed, administer Credelio Cat with food immediately and resume a monthly dosing schedule from that date on.

If you have questions or concerns about fleas and ticks due to the late/missed dose, please consult your veterinarian.

Storage

Store in a cool, dry place at a controlled room temperature (59 to 77°F, excursions permitted between 41 to 104°F). Keep out of the reach of children and pets. Tablets should remain sealed in their original packaging and should only be taken out of the blister pack at the time of dosing. Store away from heat and direct sunlight.

Do not store in the bathroom, near the kitchen sink, or in damp places. The medicine may break down if exposed to heat or moisture.

Side effects

Credelio CAT is generally well tolerated; side effects are typically mild and infrequent when given at the recommended dosage. The most common side effects of this medication are weight loss, rapid breathing, vomiting, diarrhea, decreased appetite, and elevated blood urea nitrogen (BUN).

Contact your veterinarian immediately if your pet experiences persistent vomiting, complete loss of appetite, seizures, tremors, extreme weakness, or decreased coordination (e.g., stumbling, difficulty walking).

Notify your veterinarian if your pet experiences any of the effects described above, or if you notice any other side effects that are persistent or troublesome.

If you notice anything unusual, please consult your veterinarian.

Precautions

*For complete product information including warnings and precautions, please refer to the manufacturer package insert.

For oral use in cats only- not for human use. Keep this and all drugs out of the reach of children. Keep CREDELIO CAT in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose.

Lotilaner is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Neurologic adverse reactions have been reported in cats receiving isoxazoline class drugs, even in cats without a history of neurologic disorders. Use with caution in cats with a history of neurologic disorders.

The safety of CREDELIO CAT has not been established in breeding, pregnant, and lactating cats. Discuss the risks of using this medication with your veterinarian if your pet is in one of these groups.

The effectiveness of CREDELIO CAT against Ixodes scapularis in kittens less than 6 months of age has not been evaluated.

Do not administer to animals with a known history or suspected allergy/hypersensitivity to any isoxazoline class drug, including this medication or any of its ingredients. Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies.

If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways; difficulty breathing; agitation; profuse salivation; and widespread hives or itching.

Drug and food interactions

There are no documented drug or food interactions with Credelio CAT.

Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.

Please ensure your veterinarian is aware of all medications and supplements that your pet is currently receiving. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.

Adverse reactions

If you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer Elanco US at 1-888-545-5973 or Vetsource Pet Owner Care at 877-738-4443.

Overdose

If you have any reason to suspect an overdose, call your doctor/veterinarian or the appropriate poison control resource immediately.

For humans:

The national toll-free Poison Help line, 1-800-222-1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories.

For animals:

The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888-426-4435.

Pet Poison Helpline® also provides a 24/7 animal poison control service at 855-764-7661.

*Please note: this information is for third-party services and is provided for convenience in case of potential poison-related emergencies. There may be consultation fee for these services.

Disclaimer

The content provided on this page is NOT medical advice.

All content, including the images and product description above, is intended for general informational purposes only and should not be considered a substitute for professional veterinary consultation, diagnosis, or treatment.

Consult your veterinarian for complete information about this product and how it fits into your pet's individual treatment plan.

Last revised: 8/20/2025

Description
Product details
Credelio CAT (lotilaner) is the first flea and tick chewable tablet for cats, administered once per month to kill adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) in cats and kittens 8 weeks of age and older, and weighing 2 pounds or greater. CREDELIO CAT is also indicated for the treatment and control of Ixodes scapularis (black-legged tick) infestations for one month in cats and kittens 6 months of age and older, and weighing 2 pounds or greater.
- The first flea and tick infestation prevention and treatment chewable tablet for cats & kittens 8+ weeks of age, and weighing 2 pounds or greater
- Fast-acting ingredients start killing adult fleas in just 6 hours
- Small, tasty chewable tablet made with vanilla & yeast to appeal to cats
- Works hard all month long
- Easy to give; Credelio CAT was successfully given by over 99% of cat owners (Chappell K, Paarlberg T, Seewald W, et al. A randomized, controlled field study to assess the efficacy and safety of lotilaner flavored chewable tablets (Credelio® CAT) in eliminating fleas in client-owned cats in the USA. Parasite Vector. 2021;14:127.)
Product sourced directly from the manufacturer or their approved distributor. Guaranteed genuine product backed by the manufacturer.

For
Cats (8 weeks of age and older)

Active ingredient(s)
Lotilaner

Inactive ingredients
Complete inactive ingredients list not provided by manufacturer.

Brand name
Credelio CAT

Drug class
Isoxazoline ectoparasiticide

Product flavoring
Credelio CAT is vanilla yeast flavored.
*Contains vanilla, yeast

Manufacturer
Elanco

Product strength & size

Weight range Lotilaner (per chewable tablet) Chewable tablets administered
2 to 4 lbs 12 mg One
4.1 to 17* lbs 48 mg One

*For cats over 17 lbs, administer the appropriate combination of chewable tablets to cover your pet’s body weight.

Usage
*For complete product information, please review the full prescribing information in the manufacturer package insert.

Manufacturer Dosage and Administration:
CREDELIO CAT is given orally once a month, at the minimum dosage of 2.7 mg/lb (6 mg/kg).

All owners have different comfort levels with their cat when it comes to administering medication. There are three basic ways to administer Credelio Cat:
1) Offer by hand or place in area where your cat feels comfortable eating. Many cats will eat the chewable by free choice. Tempting with treats can also help.
2) Offer with food during a meal. If your cat is a grazer, try placing it around a few pieces of kibble or covered in wet food and checking to make sure it has been consumed out of the bowl.
3) Place the chewable on the back of your cat’s tongue. The chewables were designed to be very small and easy to administer in these situations. It is important to always administer Credelio Cat with a meal or 30 minutes after feeding.

Treatment with CREDELIO CAT can begin at any time of the year and can continue year-round without interruption.

Missed doses
Treatment should be administered monthly. If a dose is missed, administer Credelio Cat with food immediately and resume a monthly dosing schedule from that date on.
If you have questions or concerns about fleas and ticks due to the late/missed dose, please consult your veterinarian.

Storage
Store in a cool, dry place at a controlled room temperature (59 to 77°F, excursions permitted between 41 to 104°F). Keep out of the reach of children and pets. Tablets should remain sealed in their original packaging and should only be taken out of the blister pack at the time of dosing. Store away from heat and direct sunlight.
Do not store in the bathroom, near the kitchen sink, or in damp places. The medicine may break down if exposed to heat or moisture.

Side effects
Credelio CAT is generally well tolerated; side effects are typically mild and infrequent when given at the recommended dosage. The most common side effects of this medication are weight loss, rapid breathing, vomiting, diarrhea, decreased appetite, and elevated blood urea nitrogen (BUN).

Contact your veterinarian immediately if your pet experiences persistent vomiting, complete loss of appetite, seizures, tremors, extreme weakness, or decreased coordination (e.g., stumbling, difficulty walking).

Notify your veterinarian if your pet experiences any of the effects described above, or if you notice any other side effects that are persistent or troublesome.
If you notice anything unusual, please consult your veterinarian.

Precautions
*For complete product information including warnings and precautions, please refer to the manufacturer package insert.

For oral use in cats only- not for human use. Keep this and all drugs out of the reach of children. Keep CREDELIO CAT in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose.

Lotilaner is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Neurologic adverse reactions have been reported in cats receiving isoxazoline class drugs, even in cats without a history of neurologic disorders. Use with caution in cats with a history of neurologic disorders.
The safety of CREDELIO CAT has not been established in breeding, pregnant, and lactating cats. Discuss the risks of using this medication with your veterinarian if your pet is in one of these groups.
The effectiveness of CREDELIO CAT against Ixodes scapularis in kittens less than 6 months of age has not been evaluated.

Do not administer to animals with a known history or suspected allergy/hypersensitivity to any isoxazoline class drug, including this medication or any of its ingredients. Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies.
If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways; difficulty breathing; agitation; profuse salivation; and widespread hives or itching.

Drug and food interactions
There are no documented drug or food interactions with Credelio CAT.
Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.

Please ensure your veterinarian is aware of all medications and supplements that your pet is currently receiving. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.

Adverse reactions
If you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer Elanco US at 1-888-545-5973 or Vetsource Pet Owner Care at 877-738-4443.

Overdose
If you have any reason to suspect an overdose, call your doctor/veterinarian or the appropriate poison control resource immediately.

For humans:
The national toll-free Poison Help line, 1-800-222-1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories.

For animals:
The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888-426-4435.
Pet Poison Helpline® also provides a 24/7 animal poison control service at 855-764-7661.

*Please note: this information is for third-party services and is provided for convenience in case of potential poison-related emergencies. There may be consultation fee for these services.

Disclaimer
The content provided on this page is NOT medical advice.
All content, including the images and product description above, is intended for general informational purposes only and should not be considered a substitute for professional veterinary consultation, diagnosis, or treatment.
Consult your veterinarian for complete information about this product and how it fits into your pet's individual treatment plan.

Last revised: 8/20/2025
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