Product details
Credelio (lotilaner) for Dogs is a beef-flavored, chewable tablet administered once per month to kill adult fleas, treat and prevent flea infestations, and treat and control tick infestations (lone star tick, American dog tick, black-legged tick, and brown dog tick) in dogs and puppies 8 weeks of age and older, and weighing 4.4 pounds or greater.
- Tick and flea treatment & infestation prevention for dogs 8 weeks of age and older, and weighing 4.4 pounds or greater
- Fast-acting ingredients start killing Ixodes ricinus ticks & adult fleas in just 4 hours
- Kills 100% of fleas in 12 hours & stays effective for 30 days
- Easy to give your dog; no greasy, messy application
- Small, beef-flavored chewable tablet accepted by 100% of dogs tested (Karadzovska D, Chappell K, Coble S, et al. A randomized, controlled field study to assess the efficacy and safety of lotilaner flavored chewable tablets (Credelio™) in eliminating fleas in client-owned dogs in the USA. Parasite Vector. 2017;10(1):528.)
Product sourced directly from the manufacturer or their approved distributor. Guaranteed genuine product backed by the manufacturer.
For
Dogs (8 weeks of age and older)
Active ingredient(s)
Lotilaner
Inactive ingredients
Complete inactive ingredients list not provided by manufacturer.
Brand name
Credelio for Dogs
Drug class
Isoxazoline ectoparasiticide
Product flavoring
Credelio for Dogs is “beef” flavored.
*Contains pork liver, soy, barley, wheat, lactose (does not contain actual beef)
Manufacturer
Elanco
Product strength & size
| Weight range | Lotilaner (per chewable tablet) | Chewable tablets administered |
|---|---|---|
| 4.4 to 6 lbs | 56.25 mg | One |
| 6.1 to 12 lbs | 112.5 mg | One |
| 12.1 to 25 lbs | 225 mg | One |
| 25.1 to 50 lbs | 450 mg | One |
| 50.1 to 100* lbs | 900 mg | One |
*For dogs over 100 lbs, administer the appropriate combination of chewable tablets to cover your pet’s body weight.
Usage
*For complete product information, please review the full prescribing information in the manufacturer package insert.
Manufacturer Dosage and Administration:
Credelio is given orally once a month, at the minimum dosage of 9 mg/lb (20 mg/kg).
Credelio must be administered with food or given within 30 minutes of feeding.
Treatment with Credelio can begin at any time of the year and can continue year-round without interruption.
Missed doses
If a dose is missed, administer Credelio with food and resume a monthly dosing schedule to minimize the opportunity for tick and flea re-infestations. Consult your veterinarian about any concerns you may have about ticks and fleas due to the late/missed dose.
Storage
Store in a cool, dry place at a controlled room temperature (59 to 77°F, excursions permitted between 41 to 104°F). Keep out of the reach of children and pets. Tablets should remain sealed in their original packaging and should only be taken out of the blister pack at the time of dosing. Store away from heat and direct sunlight.
Do not store in the bathroom, near the kitchen sink, or in damp places. The medicine may break down if exposed to heat or moisture.
Side effects
Credelio is generally well tolerated, and side effects are considered uncommon when given at the recommended dosage. The most common side effects of this medication are vomiting, diarrhea, decreased appetite, weight loss, elevated blood urea nitrogen (BUN), and increased urination.
Contact your veterinarian immediately if your pet experiences persistent vomiting, complete loss of appetite, or if you notice your pet has a seizure, tremors, extreme weakness, or decreased coordination (e.g., stumbling, difficulty walking).
Notify your veterinarian if your pet experiences any of the effects described above, or if you notice any other side effects that are persistent or troublesome.
If you notice anything unusual, please consult your veterinarian.
Precautions
*For complete product information including warnings and precautions, please refer to the manufacturer package insert.
For oral use in dogs only- not for human use. Keep this and all drugs out of the reach of children. Keep Credelio in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose.
Lotilaner is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders.
The safe use of Credelio in breeding, pregnant, or lactating dogs has not been evaluated. Discuss the risks of using this medication with your veterinarian if your pet is in one of these groups.
Do not administer to animals with a known history or suspected allergy/hypersensitivity to any isoxazoline class drug, including this medication or any of its ingredients. Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies.
If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways; difficulty breathing; agitation; profuse salivation; and widespread hives or itching.
Drug and food interactions
There are no documented drug or food interactions with Credelio for Dogs.
Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.
Please ensure your veterinarian is aware of all medications and supplements that your pet is currently receiving. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.
Adverse reactions
If you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer Elanco US at 1-888-545-5973 or Vetsource Pet Owner Care at 877-738-4443.
Overdose
If you have any reason to suspect an overdose, call your doctor/veterinarian or the appropriate poison control resource immediately.
For humans:
The national toll-free Poison Help line, 1-800-222-1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories.
For animals:
The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888-426-4435.
Pet Poison Helpline® also provides a 24/7 animal poison control service at 855-764-7661.
*Please note: this information is for third-party services and is provided for convenience in case of potential poison-related emergencies. There may be consultation fee for these services.
Disclaimer
The content provided on this page is NOT medical advice.
All content, including the images and product description above, is intended for general informational purposes only and should not be considered a substitute for professional veterinary consultation, diagnosis, or treatment.
Consult your veterinarian for complete information about this product and how it fits into your pet's individual treatment plan.
Last revised: 8/19/2025
-
Description
Product detailsCredelio (lotilaner) for Dogs is a beef-flavored, chewable tablet administered once per month to kill adult fleas, treat and prevent flea infestations, and treat and control tick infestations (lone star tick, American dog tick, black-legged tick, and brown dog tick) in dogs and puppies 8 weeks of age and older, and weighing 4.4 pounds or greater.- Tick and flea treatment & infestation prevention for dogs 8 weeks of age and older, and weighing 4.4 pounds or greater
- Fast-acting ingredients start killing Ixodes ricinus ticks & adult fleas in just 4 hours
- Kills 100% of fleas in 12 hours & stays effective for 30 days
- Easy to give your dog; no greasy, messy application
- Small, beef-flavored chewable tablet accepted by 100% of dogs tested (Karadzovska D, Chappell K, Coble S, et al. A randomized, controlled field study to assess the efficacy and safety of lotilaner flavored chewable tablets (Credelio™) in eliminating fleas in client-owned dogs in the USA. Parasite Vector. 2017;10(1):528.)
Product sourced directly from the manufacturer or their approved distributor. Guaranteed genuine product backed by the manufacturer.ForDogs (8 weeks of age and older)Active ingredient(s)LotilanerInactive ingredientsComplete inactive ingredients list not provided by manufacturer.Brand nameCredelio for DogsDrug classIsoxazoline ectoparasiticideProduct flavoringCredelio for Dogs is “beef” flavored.*Contains pork liver, soy, barley, wheat, lactose (does not contain actual beef)ManufacturerElancoProduct strength & sizeWeight range Lotilaner (per chewable tablet) Chewable tablets administered 4.4 to 6 lbs 56.25 mg One 6.1 to 12 lbs 112.5 mg One 12.1 to 25 lbs 225 mg One 25.1 to 50 lbs 450 mg One 50.1 to 100* lbs 900 mg One *For dogs over 100 lbs, administer the appropriate combination of chewable tablets to cover your pet’s body weight.Usage*For complete product information, please review the full prescribing information in the manufacturer package insert.Manufacturer Dosage and Administration:Credelio is given orally once a month, at the minimum dosage of 9 mg/lb (20 mg/kg).Credelio must be administered with food or given within 30 minutes of feeding.Treatment with Credelio can begin at any time of the year and can continue year-round without interruption.Missed dosesIf a dose is missed, administer Credelio with food and resume a monthly dosing schedule to minimize the opportunity for tick and flea re-infestations. Consult your veterinarian about any concerns you may have about ticks and fleas due to the late/missed dose.StorageStore in a cool, dry place at a controlled room temperature (59 to 77°F, excursions permitted between 41 to 104°F). Keep out of the reach of children and pets. Tablets should remain sealed in their original packaging and should only be taken out of the blister pack at the time of dosing. Store away from heat and direct sunlight.Do not store in the bathroom, near the kitchen sink, or in damp places. The medicine may break down if exposed to heat or moisture.Side effectsCredelio is generally well tolerated, and side effects are considered uncommon when given at the recommended dosage. The most common side effects of this medication are vomiting, diarrhea, decreased appetite, weight loss, elevated blood urea nitrogen (BUN), and increased urination.Contact your veterinarian immediately if your pet experiences persistent vomiting, complete loss of appetite, or if you notice your pet has a seizure, tremors, extreme weakness, or decreased coordination (e.g., stumbling, difficulty walking).Notify your veterinarian if your pet experiences any of the effects described above, or if you notice any other side effects that are persistent or troublesome.If you notice anything unusual, please consult your veterinarian.Precautions*For complete product information including warnings and precautions, please refer to the manufacturer package insert.For oral use in dogs only- not for human use. Keep this and all drugs out of the reach of children. Keep Credelio in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose.Lotilaner is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders.The safe use of Credelio in breeding, pregnant, or lactating dogs has not been evaluated. Discuss the risks of using this medication with your veterinarian if your pet is in one of these groups.Do not administer to animals with a known history or suspected allergy/hypersensitivity to any isoxazoline class drug, including this medication or any of its ingredients. Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies.If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways; difficulty breathing; agitation; profuse salivation; and widespread hives or itching.Drug and food interactionsThere are no documented drug or food interactions with Credelio for Dogs.Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.Please ensure your veterinarian is aware of all medications and supplements that your pet is currently receiving. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.Adverse reactionsIf you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer Elanco US at 1-888-545-5973 or Vetsource Pet Owner Care at 877-738-4443.OverdoseIf you have any reason to suspect an overdose, call your doctor/veterinarian or the appropriate poison control resource immediately.For humans:The national toll-free Poison Help line, 1-800-222-1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories.For animals:The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888-426-4435.Pet Poison Helpline® also provides a 24/7 animal poison control service at 855-764-7661.*Please note: this information is for third-party services and is provided for convenience in case of potential poison-related emergencies. There may be consultation fee for these services.DisclaimerThe content provided on this page is NOT medical advice.All content, including the images and product description above, is intended for general informational purposes only and should not be considered a substitute for professional veterinary consultation, diagnosis, or treatment.Consult your veterinarian for complete information about this product and how it fits into your pet's individual treatment plan.Last revised: 8/19/2025 -
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