Product details
IVERHART PLUS® Flavored Chewables are indicated for use in dogs to prevent canine heartworm disease by eliminating the tissue stage of heartworm larvae (Dirofilaria immitis) for a month (30 days) after infection and for the treatment and control of roundworms (Toxocara canis, Toxascaris leonina) and hookworms (Ancylostoma caninum, Uncinaria stenocephala, Ancylostoma braziliense).
Please note: The manufacturer is updating the packaging and label for this product; there are no changes to the product itself. The packaging of your ordered product may vary depending on current manufacturer availability.
- Just one IVERHART PLUS (ivermectin/pyrantel) Flavored Chewable given monthly protects your dog from heartworm disease and treats and controls roundworms and hookworms
- This flavored chewable is tasty and safe, even in puppies as young as 6 weeks
- Available in three sizes: Small (Up to 25 lbs), Medium (26-50 lbs), and Large (51-100 lbs)
- Tasty pork liver flavor makes dosing easy
- This formula provides effective protection against heartworms, roundworms, and hookworms at an excellent value
Product sourced directly from the manufacturer or their approved distributor. Guaranteed genuine product backed by the manufacturer.
For
Dogs (6 weeks of age and older)
Active ingredient(s)
Ivermectin, Pyrantel pamoate
Inactive ingredients
Complete inactive ingredients list not provided by manufacturer.
Brand name
IVERHART PLUS
Drug class
Avermectin antiparasitic, Tetrahydropyrimidine anthelmintic
Product flavoring
Iverhart PLUS Flavored Chewables are pork liver flavored*.
*Contains an ingredient derived from pork (liver).
Manufacturer
Virbac
Product strength & size
| Dog weight | Flavored chewables per month | Ivermectin content | Pyrantel content | Color coding on carton |
|---|---|---|---|---|
| 0 - 25 lbs | One | 68 mcg | 57 mg | Blue |
| 26 - 50 lbs | One | 136 mcg | 114 mg | Green |
| 51 - 100 lbs* | One | 272 mcg | 227 mg | Brown |
*For dogs over 100 lbs, use the appropriate combination of flavored chewables to cover your pet’s body weight.
Usage
For additional product information, please refer to the product label and the full Prescribing Information provided in the manufacturer’s package insert.
Iverhart PLUS should be given orally at monthly intervals year-round, or as otherwise directed by your veterinarian.
Manufacturer recommended usage:
IVERHART PLUS (ivermectin/pyrantel) Flavored Chewables should be administered orally at monthly intervals at the recommended minimum dose level of 6 mcg of ivermectin per kilogram (2.72 mcg/lb) and 5 mg of pyrantel (as pamoate salt) per kg (2.27 mg/lb) of body weight.
Remove only one chewable at a time from the foil-backed blister card. Return the card with the remaining chewables to its box to protect the product from light.
Because most dogs find IVERHART PLUS Flavored Chewables palatable, the product can be offered to the dog by hand. To avoid the risk of choking or intestinal obstruction, the chewable should be administered in a manner that encourages the dog to chew, rather than to swallow without chewing. Chewables may be broken into pieces and fed to dogs that normally swallow treats whole. Alternatively, it may be added intact to a small amount of dog food to encourage chewing, but care should be taken to ensure that the dog consumes the complete dose at one time.
Treated animals should be observed for a few minutes after administration to ensure that part of the dose is not lost or rejected. If it is suspected that any of the dose has been lost, redosing is recommended.
Missed doses
If a dose is missed: give IVERHART PLUS immediately to resume monthly dosing and notify your veterinarian. Do not give two doses at once.
If multiple doses have been missed, consult your veterinarian prior to restarting the monthly dosing schedule. If you have questions about your pet’s prescribed dosing schedule (e.g., timing, interval), please contact your veterinarian.
Storage
Store in a cool, dry place at a controlled room temperature (68-77°F, excursions permitted between 59 and 86°F). Keep in a secure location out of the reach of children and pets. Protect this product from light.
Remove only one chewable at a time from the foil-backed blister card. Return the card with the remaining chewables to its box to protect the product from light. Tablets should remain sealed in their original packaging and only taken out of the blister pack at the time of dosing.
Exposure to extreme temperatures or moisture may affect the integrity and effectiveness of medications. Always store medications properly (e.g., away from the bathroom, kitchen sink, or other damp places).
Side effects
For additional product information regarding potential side effects, please refer to the product label and Prescribing Information.
IVERHART PLUS is well tolerated, and side effects are considered uncommon when given at the recommended dosage. The most common side effects of this medication are vomiting and diarrhea.
In rare cases, digestive or neurological side effects have been reported following the use of IVERHART PLUS Flavored Chewables. These effects include (but may not be limited to) lethargy, decreased appetite, seizures, ataxia (decreased muscle coordination), muscle tremors, hypersalivation (drooling), and itching.
Contact your veterinarian immediately if your pet experiences severe/excessive drooling, seizures or tremors, or exhibits decreased coordination (e.g., staggering, stumbling, difficulty walking).
Notify your veterinarian if your pet experiences any of the effects described above, or if you notice any other side effects that are persistent or troublesome.
If you notice anything unusual, please consult your veterinarian.
Precautions
Before using this product, please review the product label and full Prescribing Information for important safety information, including any relevant warnings and precautions.
For use in dogs only. Keep this and all drugs out of the reach of children and animals.
All dogs should be tested for existing heartworm infection before starting treatment with IVERHART PLUS Flavored Chewables, which are not effective against adult D. immitis. Infected dogs must be treated to remove adult heartworms and microfilariae before initiating a program with IVERHART PLUS Flavored Chewables.
While some microfilariae may be killed by the ivermectin in IVERHART PLUS Flavored Chewables at the recommended dose level, IVERHART PLUS Flavored Chewables are not effective for microfilariae clearance. A mild hypersensitivity-type reaction, presumably due to dead or dying microfilariae and particularly involving a transient diarrhea, has been observed in clinical trials with ivermectin alone after treatment of some dogs that have circulating microfilariae.
Choking or intestinal obstruction has been reported after dosing with ivermectin/pyrantel. For dogs that normally swallow treats whole, chewables may be broken into pieces.
Do not administer IVERHART PLUS to animals with a known history or suspected allergy/hypersensitivity to any avermectin or tetrahydropyrimidine drug, including this medication or any of its ingredients. Allergic reactions to medications may occur. Please inform Vetsource and your veterinarian if your pet has any known sensitivities or allergies, especially to medications and supplements.
If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways; difficulty breathing; agitation; profuse salivation; and widespread hives or itching.
Drug and food interactions
While there are no documented drug or food interactions with this medication when given at the recommended dosage, potential interactions may still be possible.
Contact your veterinarian if your pet experiences any unusual reactions when multiple medications and/or supplements are given together.
Please ensure your veterinarian is aware of all medications, supplements, and over-the-counter (OTC) products that your pet is currently using. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.
Adverse reactions
If you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer Virbac AH at 1-800-338-3659 or Vetsource Pet Owner Care at 877-738-4443.
Overdose
If you have any reason to suspect an overdose, call your doctor/veterinarian or the appropriate poison control resource immediately.
For humans:
The national toll-free Poison Help line, 1-800-222-1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories.
For animals:
The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888-426-4435.
Pet Poison Helpline® also provides a 24/7 animal poison control service at 855-764-7661.
*Please note: this information is for third-party services and is provided for convenience in case of potential poison-related emergencies. There may be consultation fee for these services.
Disclaimer
The content provided on this page is NOT medical advice.
All content, including the images and product description above, is intended for general informational purposes only and should not be considered a substitute for professional veterinary consultation, diagnosis, or treatment.
Consult your veterinarian for complete information about this product and how it fits into your pet's individual treatment plan.
Last revised: 1/16/2026
-
Description
Product detailsIVERHART PLUS® Flavored Chewables are indicated for use in dogs to prevent canine heartworm disease by eliminating the tissue stage of heartworm larvae (Dirofilaria immitis) for a month (30 days) after infection and for the treatment and control of roundworms (Toxocara canis, Toxascaris leonina) and hookworms (Ancylostoma caninum, Uncinaria stenocephala, Ancylostoma braziliense).Please note: The manufacturer is updating the packaging and label for this product; there are no changes to the product itself. The packaging of your ordered product may vary depending on current manufacturer availability.- Just one IVERHART PLUS (ivermectin/pyrantel) Flavored Chewable given monthly protects your dog from heartworm disease and treats and controls roundworms and hookworms
- This flavored chewable is tasty and safe, even in puppies as young as 6 weeks
- Available in three sizes: Small (Up to 25 lbs), Medium (26-50 lbs), and Large (51-100 lbs)
- Tasty pork liver flavor makes dosing easy
- This formula provides effective protection against heartworms, roundworms, and hookworms at an excellent value
Product sourced directly from the manufacturer or their approved distributor. Guaranteed genuine product backed by the manufacturer.ForDogs (6 weeks of age and older)Active ingredient(s)Ivermectin, Pyrantel pamoateInactive ingredientsComplete inactive ingredients list not provided by manufacturer.Brand nameIVERHART PLUSDrug classAvermectin antiparasitic, Tetrahydropyrimidine anthelminticProduct flavoringIverhart PLUS Flavored Chewables are pork liver flavored*.*Contains an ingredient derived from pork (liver).ManufacturerVirbacProduct strength & sizeDog weight Flavored chewables per month Ivermectin content Pyrantel content Color coding on carton 0 - 25 lbs One 68 mcg 57 mg Blue 26 - 50 lbs One 136 mcg 114 mg Green 51 - 100 lbs* One 272 mcg 227 mg Brown *For dogs over 100 lbs, use the appropriate combination of flavored chewables to cover your pet’s body weight.UsageFor additional product information, please refer to the product label and the full Prescribing Information provided in the manufacturer’s package insert.Iverhart PLUS should be given orally at monthly intervals year-round, or as otherwise directed by your veterinarian.Manufacturer recommended usage:IVERHART PLUS (ivermectin/pyrantel) Flavored Chewables should be administered orally at monthly intervals at the recommended minimum dose level of 6 mcg of ivermectin per kilogram (2.72 mcg/lb) and 5 mg of pyrantel (as pamoate salt) per kg (2.27 mg/lb) of body weight.Remove only one chewable at a time from the foil-backed blister card. Return the card with the remaining chewables to its box to protect the product from light.Because most dogs find IVERHART PLUS Flavored Chewables palatable, the product can be offered to the dog by hand. To avoid the risk of choking or intestinal obstruction, the chewable should be administered in a manner that encourages the dog to chew, rather than to swallow without chewing. Chewables may be broken into pieces and fed to dogs that normally swallow treats whole. Alternatively, it may be added intact to a small amount of dog food to encourage chewing, but care should be taken to ensure that the dog consumes the complete dose at one time.Treated animals should be observed for a few minutes after administration to ensure that part of the dose is not lost or rejected. If it is suspected that any of the dose has been lost, redosing is recommended.Missed dosesIf a dose is missed: give IVERHART PLUS immediately to resume monthly dosing and notify your veterinarian. Do not give two doses at once.If multiple doses have been missed, consult your veterinarian prior to restarting the monthly dosing schedule. If you have questions about your pet’s prescribed dosing schedule (e.g., timing, interval), please contact your veterinarian.StorageStore in a cool, dry place at a controlled room temperature (68-77°F, excursions permitted between 59 and 86°F). Keep in a secure location out of the reach of children and pets. Protect this product from light.Remove only one chewable at a time from the foil-backed blister card. Return the card with the remaining chewables to its box to protect the product from light. Tablets should remain sealed in their original packaging and only taken out of the blister pack at the time of dosing.Exposure to extreme temperatures or moisture may affect the integrity and effectiveness of medications. Always store medications properly (e.g., away from the bathroom, kitchen sink, or other damp places).Side effectsFor additional product information regarding potential side effects, please refer to the product label and Prescribing Information.IVERHART PLUS is well tolerated, and side effects are considered uncommon when given at the recommended dosage. The most common side effects of this medication are vomiting and diarrhea.In rare cases, digestive or neurological side effects have been reported following the use of IVERHART PLUS Flavored Chewables. These effects include (but may not be limited to) lethargy, decreased appetite, seizures, ataxia (decreased muscle coordination), muscle tremors, hypersalivation (drooling), and itching.Contact your veterinarian immediately if your pet experiences severe/excessive drooling, seizures or tremors, or exhibits decreased coordination (e.g., staggering, stumbling, difficulty walking).Notify your veterinarian if your pet experiences any of the effects described above, or if you notice any other side effects that are persistent or troublesome.If you notice anything unusual, please consult your veterinarian.PrecautionsBefore using this product, please review the product label and full Prescribing Information for important safety information, including any relevant warnings and precautions.For use in dogs only. Keep this and all drugs out of the reach of children and animals.All dogs should be tested for existing heartworm infection before starting treatment with IVERHART PLUS Flavored Chewables, which are not effective against adult D. immitis. Infected dogs must be treated to remove adult heartworms and microfilariae before initiating a program with IVERHART PLUS Flavored Chewables.While some microfilariae may be killed by the ivermectin in IVERHART PLUS Flavored Chewables at the recommended dose level, IVERHART PLUS Flavored Chewables are not effective for microfilariae clearance. A mild hypersensitivity-type reaction, presumably due to dead or dying microfilariae and particularly involving a transient diarrhea, has been observed in clinical trials with ivermectin alone after treatment of some dogs that have circulating microfilariae.Choking or intestinal obstruction has been reported after dosing with ivermectin/pyrantel. For dogs that normally swallow treats whole, chewables may be broken into pieces.Do not administer IVERHART PLUS to animals with a known history or suspected allergy/hypersensitivity to any avermectin or tetrahydropyrimidine drug, including this medication or any of its ingredients. Allergic reactions to medications may occur. Please inform Vetsource and your veterinarian if your pet has any known sensitivities or allergies, especially to medications and supplements.If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways; difficulty breathing; agitation; profuse salivation; and widespread hives or itching.Drug and food interactionsWhile there are no documented drug or food interactions with this medication when given at the recommended dosage, potential interactions may still be possible.Contact your veterinarian if your pet experiences any unusual reactions when multiple medications and/or supplements are given together.Please ensure your veterinarian is aware of all medications, supplements, and over-the-counter (OTC) products that your pet is currently using. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.Adverse reactionsIf you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer Virbac AH at 1-800-338-3659 or Vetsource Pet Owner Care at 877-738-4443.OverdoseIf you have any reason to suspect an overdose, call your doctor/veterinarian or the appropriate poison control resource immediately.For humans:The national toll-free Poison Help line, 1-800-222-1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories.For animals:The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888-426-4435.Pet Poison Helpline® also provides a 24/7 animal poison control service at 855-764-7661.*Please note: this information is for third-party services and is provided for convenience in case of potential poison-related emergencies. There may be consultation fee for these services.DisclaimerThe content provided on this page is NOT medical advice.All content, including the images and product description above, is intended for general informational purposes only and should not be considered a substitute for professional veterinary consultation, diagnosis, or treatment.Consult your veterinarian for complete information about this product and how it fits into your pet's individual treatment plan.Last revised: 1/16/2026 -
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