Product Information

Description

Product details

NexGard (afoxolaner) flea and tick protection chewable for dogs is FDA-approved to prevent infections that cause Lyme disease as a result of killing black-legged ticks. Vet-recommended and #1 dog-preferred.^1,2 You’ll love protecting your dog with a treatment that prevents flea infestations month after month.

Vet-recommended flea and tick control that kills fleas fast, before they can lay eggs.¹
This flea and tick treatment product is FDA-approved to prevent Lyme infections as a direct result of killing black-legged ticks.
Kills fleas and ticks all month long.
NexGard (afoxolaner) flea and tick chewables are #1 dog-preferred and have a delicious beef flavor.^2,3
Safe for dogs and puppies as young as 8 weeks, weighing 4 pounds or more.

With one little NexGard (afoxolaner) chew comes the confidence that you’re giving your dog vet-recommended flea and tick control¹. Numerous studies have proven that NexGard is both an effective and safe oral treatment for flea and tick protection. NexGard flea and tick control chewable is approved by the FDA to prevent infections that cause Lyme disease in dogs as a result of killing black-legged ticks. And each bite-sized monthly flea and tick treatment dose is safe to give to puppies and dogs as young as 8 weeks, weighing as little as 4 pounds.

NexGard chews are #1 dog preferred and have a delicious beef flavor. And because you should feel just as good about the medicine your dog receives as he does taking it, the ingredients in each NexGard flea and tick protection chew have been carefully designed to quickly kill fleas and ticks for a full month, killing fleas before they have a chance to lay eggs and black-legged ticks before they transmit Lyme infections. NexGard chews are flea and tick control for dogs that are easy to give, effective, and enjoyable, month after month.

References:

1. Data on file at Boehringer Ingelheim.

2. Data on file at Boehringer Ingelheim.

3. Data on file at Boehringer Ingelheim.

Product sourced directly from the manufacturer or their approved distributor. Guaranteed genuine product backed by the manufacturer.

For

Dogs (8 weeks of age and older)

Active ingredient(s)

Afoxolaner

Inactive ingredients

Complete inactive ingredients list not provided by manufacturer.

Brand name

NexGard Chewables

Drug class

Isoxazoline ectoparasiticide

Product flavoring

NexGard Chewables are beef flavored.

*Contains soy; NexGard Chewables are gluten-free and do not contain actual beef.

Manufacturer

Boehringer Ingelheim Animal Health USA

Product strength & size

Weight Range	Afoxolaner (per chewable)	Chewables Administered
4 to 10 lbs.	11.3 mg	One
10.1 to 24 lbs.	28.3 mg	One
24.1 to 60 lbs.	68 mg	One
60.1 to 121 lbs.	136 mg	One

*For dogs over 121 lbs., administer the appropriate combination of chewables to cover your pet’s body weight.

Usage

*For complete product information, please review the full prescribing information in the manufacturer package insert.

Manufacturer recommended usage:

NexGard (afoxolaner) chews are given orally once a month, at the minimum dosage of 1.14 mg/lb (2.5 mg/kg).

NexGard chews can be administered with or without food. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. If it is suspected that any of the dose has been lost or if vomiting occurs within two hours of administration, redose with another full dose. If a dose is missed, administer NexGard chew and resume a monthly dosing schedule.

Flea Treatment and Protection: Treatment with NexGard chews may begin at any time of the year. In areas where fleas are common year-round, monthly treatment with NexGard should continue the entire year without interruption.

To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea control product.

Tick Treatment and Control: Treatment with NexGard chews may begin at any time of the year.

Missed doses

If a dose is missed: administer NexGard chew immediately and resume a monthly dosing schedule. Do not give two doses at once.

Storage

Store in a cool, dry place at a controlled room temperature (at or below 86°F, with excursions permitted up to 104°F). Keep this medication in its original packaging and out of the reach of children and pets. Only remove 1 tablet at a time from the foil-backed blister card and return the card to the box to protect from light. Tablets should remain sealed and only taken out of the blister pack at the time of dosing.

Store away from heat and direct sunlight. Do not store in the bathroom, near the kitchen sink, or in damp places. The medicine may break down if exposed to heat or moisture.

Side effects

NexGard Chewables are generally well tolerated, and side effects are considered uncommon when given at the recommended dosage. The most common side effects of this medication are vomiting, dry/flaky skin, diarrhea, lethargy, and decreased appetite.

Contact your veterinarian immediately if your pet experiences severe or persistent vomiting, complete loss of appetite, has a seizure or any other neurologic adverse reaction (e.g., tremors, hyperactivity, loss of coordination), or if any signs of a hypersensitivity reaction (e.g., hives, swelling) occur.

Notify your veterinarian if your pet experiences any of the effects described above, or if you notice any other side effects that are persistent or troublesome.

If you notice anything unusual, please consult your veterinarian.

Precautions

*For complete product information including warnings and precautions, please refer to the manufacturer package insert.

For oral use in dogs only- not for use in humans. Keep this and all drugs out of the reach of children. In case of accidental ingestion, contact a physician immediately.

Keep NexGard chews in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose.

Afoxolaner is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders.

The safe use of NexGard (afoxolaner) in breeding, pregnant, or lactating dogs has not been evaluated.

Do not administer to animals with a known history or suspected allergy/hypersensitivity to any isoxazoline class drug, including this medication or any of its ingredients. Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies.

If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways; difficulty breathing; agitation; profuse salivation; and widespread hives or itching.

Drug and food interactions

There are no documented drug or food interactions with this medication.

Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.

Please ensure your veterinarian is aware of all medications and supplements that your pet is currently receiving. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.

Adverse reactions

If you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer Boehringer Ingelheim Animal Health USA at 1-888-637-4251 or Vetsource Pet Owner Care at 877-738-4443.

Overdose

If you have any reason to suspect an overdose, call your doctor/veterinarian or the appropriate poison control resource immediately.

For humans:

The national toll-free Poison Help line, 1-800-222-1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories.

For animals:

The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888-426-4435.

Pet Poison Helpline® also provides a 24/7 animal poison control service at 855-764-7661.

*Please note: this information is for third-party services and is provided for convenience in case of potential poison-related emergencies. There may be consultation fee for these services.

Disclaimer

The content provided on this page is NOT medical advice.

All content, including the images and product description above, is intended for general informational purposes only and should not be considered a substitute for professional veterinary consultation, diagnosis, or treatment.

Consult your veterinarian for complete information about this product and how it fits into your pet's individual treatment plan.

Last revised: 7/22/2025

Description
Product details
NexGard (afoxolaner) flea and tick protection chewable for dogs is FDA-approved to prevent infections that cause Lyme disease as a result of killing black-legged ticks. Vet-recommended and #1 dog-preferred.^1,2 You’ll love protecting your dog with a treatment that prevents flea infestations month after month.
- Vet-recommended flea and tick control that kills fleas fast, before they can lay eggs.¹
- This flea and tick treatment product is FDA-approved to prevent Lyme infections as a direct result of killing black-legged ticks.
- Kills fleas and ticks all month long.
- NexGard (afoxolaner) flea and tick chewables are #1 dog-preferred and have a delicious beef flavor.^2,3
- Safe for dogs and puppies as young as 8 weeks, weighing 4 pounds or more.
With one little NexGard (afoxolaner) chew comes the confidence that you’re giving your dog vet-recommended flea and tick control¹. Numerous studies have proven that NexGard is both an effective and safe oral treatment for flea and tick protection. NexGard flea and tick control chewable is approved by the FDA to prevent infections that cause Lyme disease in dogs as a result of killing black-legged ticks. And each bite-sized monthly flea and tick treatment dose is safe to give to puppies and dogs as young as 8 weeks, weighing as little as 4 pounds.

NexGard chews are #1 dog preferred and have a delicious beef flavor. And because you should feel just as good about the medicine your dog receives as he does taking it, the ingredients in each NexGard flea and tick protection chew have been carefully designed to quickly kill fleas and ticks for a full month, killing fleas before they have a chance to lay eggs and black-legged ticks before they transmit Lyme infections. NexGard chews are flea and tick control for dogs that are easy to give, effective, and enjoyable, month after month.

References:
1. Data on file at Boehringer Ingelheim.
2. Data on file at Boehringer Ingelheim.
3. Data on file at Boehringer Ingelheim.

Product sourced directly from the manufacturer or their approved distributor. Guaranteed genuine product backed by the manufacturer.

For
Dogs (8 weeks of age and older)

Active ingredient(s)
Afoxolaner

Inactive ingredients
Complete inactive ingredients list not provided by manufacturer.

Brand name
NexGard Chewables

Drug class
Isoxazoline ectoparasiticide

Product flavoring
NexGard Chewables are beef flavored.
*Contains soy; NexGard Chewables are gluten-free and do not contain actual beef.

Manufacturer
Boehringer Ingelheim Animal Health USA

Product strength & size

Weight Range Afoxolaner (per chewable) Chewables Administered
4 to 10 lbs. 11.3 mg One
10.1 to 24 lbs. 28.3 mg One
24.1 to 60 lbs. 68 mg One
60.1 to 121 lbs. 136 mg One

*For dogs over 121 lbs., administer the appropriate combination of chewables to cover your pet’s body weight.

Usage
*For complete product information, please review the full prescribing information in the manufacturer package insert.

Manufacturer recommended usage:
NexGard (afoxolaner) chews are given orally once a month, at the minimum dosage of 1.14 mg/lb (2.5 mg/kg).

NexGard chews can be administered with or without food. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. If it is suspected that any of the dose has been lost or if vomiting occurs within two hours of administration, redose with another full dose. If a dose is missed, administer NexGard chew and resume a monthly dosing schedule.

Flea Treatment and Protection: Treatment with NexGard chews may begin at any time of the year. In areas where fleas are common year-round, monthly treatment with NexGard should continue the entire year without interruption.
To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea control product.

Tick Treatment and Control: Treatment with NexGard chews may begin at any time of the year.

Missed doses
If a dose is missed: administer NexGard chew immediately and resume a monthly dosing schedule. Do not give two doses at once.

Storage
Store in a cool, dry place at a controlled room temperature (at or below 86°F, with excursions permitted up to 104°F). Keep this medication in its original packaging and out of the reach of children and pets. Only remove 1 tablet at a time from the foil-backed blister card and return the card to the box to protect from light. Tablets should remain sealed and only taken out of the blister pack at the time of dosing.
Store away from heat and direct sunlight. Do not store in the bathroom, near the kitchen sink, or in damp places. The medicine may break down if exposed to heat or moisture.

Side effects
NexGard Chewables are generally well tolerated, and side effects are considered uncommon when given at the recommended dosage. The most common side effects of this medication are vomiting, dry/flaky skin, diarrhea, lethargy, and decreased appetite.

Contact your veterinarian immediately if your pet experiences severe or persistent vomiting, complete loss of appetite, has a seizure or any other neurologic adverse reaction (e.g., tremors, hyperactivity, loss of coordination), or if any signs of a hypersensitivity reaction (e.g., hives, swelling) occur.

Notify your veterinarian if your pet experiences any of the effects described above, or if you notice any other side effects that are persistent or troublesome.
If you notice anything unusual, please consult your veterinarian.

Precautions
*For complete product information including warnings and precautions, please refer to the manufacturer package insert.

For oral use in dogs only- not for use in humans. Keep this and all drugs out of the reach of children. In case of accidental ingestion, contact a physician immediately.
Keep NexGard chews in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose.

Afoxolaner is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders.
The safe use of NexGard (afoxolaner) in breeding, pregnant, or lactating dogs has not been evaluated.

Do not administer to animals with a known history or suspected allergy/hypersensitivity to any isoxazoline class drug, including this medication or any of its ingredients. Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies.
If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways; difficulty breathing; agitation; profuse salivation; and widespread hives or itching.

Drug and food interactions
There are no documented drug or food interactions with this medication.
Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.

Please ensure your veterinarian is aware of all medications and supplements that your pet is currently receiving. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.

Adverse reactions
If you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer Boehringer Ingelheim Animal Health USA at 1-888-637-4251 or Vetsource Pet Owner Care at 877-738-4443.

Overdose
If you have any reason to suspect an overdose, call your doctor/veterinarian or the appropriate poison control resource immediately.

For humans:
The national toll-free Poison Help line, 1-800-222-1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories.

For animals:
The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888-426-4435.
Pet Poison Helpline® also provides a 24/7 animal poison control service at 855-764-7661.

*Please note: this information is for third-party services and is provided for convenience in case of potential poison-related emergencies. There may be consultation fee for these services.

Disclaimer
The content provided on this page is NOT medical advice.
All content, including the images and product description above, is intended for general informational purposes only and should not be considered a substitute for professional veterinary consultation, diagnosis, or treatment.
Consult your veterinarian for complete information about this product and how it fits into your pet's individual treatment plan.

Last revised: 7/22/2025
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