Product details
PancrePlus is a pancreatic enzyme concentrate of porcine origin. It is indicated for use as a digestive aid in replacement therapy where digestion of protein, carbohydrate, and fat is inadequate due to exocrine pancreatic insufficiency.
This product is an oral tablet formulation (not powder).
- Prescription tablets containing enzymes that aid in digestion for dogs and cats with Exocrine Pancreatic Insufficiency (EPI)
- Helps pets lacking the necessary enzymes digest proteins, carbohydrates, and fats from their meals
- Provides consistent digestive support that is easy to administer
- Available in both powder and tablet forms, with a palatable porcine base
- Made in the USA
Product sourced directly from the manufacturer or their approved distributor. Guaranteed genuine product backed by the manufacturer.
For
Dogs and Cats
Active ingredient(s)
Pancrelipase (Lipase, Protease, Amylase)
Inactive ingredients
Complete inactive ingredients list not provided by manufacturer.
Brand name
PancrePlus Tablets
Drug class
Pancreatic enzymes
Product flavoring
The manufacturer does not provide specific flavoring information for this product.*
*The pancreatic enzyme concentrate in this medication is derived from porcine (pork) sources. Consult your veterinarian before using this product if your pet has an allergy to pork products.
Manufacturer
Neogen
Product strength & size
Each tablet contains a minimum of:
Lipase 9,000 USP units
Protease 57,000 USP units
Amylase 64,000 USP units
Please ensure the selected product and quantity are appropriate for your pet, as recommended by your veterinarian. For current availability, please refer to the product selection above.
Usage
For additional product information, please refer to the product label and the full Prescribing Information provided in the manufacturer’s package insert.
PancrePlus Tablets should be administered as directed by your veterinarian. Wash your hands immediately after handling. Please consult your veterinarian before making any changes or discontinuing the prescribed dosing schedule.
PancrePlus Tablets are not intended to be mixed directly with food. After administering a dose, follow immediately with food or water to reduce the risk of damage to the throat/esophagus.
Manufacturer Dosage and Administration:
PancrePlus Tablets should be administered before each meal. Your veterinarian will determine the appropriate dosage according to the severity of the condition and weight of the animal.
Average dose/meal:
Dogs: 2 - 3 tablets
Cats: 1/2 - 1 tablet
Missed doses
Administer the dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not give more medication than prescribed or two doses at once.
If you have questions about your pet’s prescribed dosing schedule (e.g., timing, interval), please consult your veterinarian.
Storage
Store in a cool, dry place at a controlled room temperature not exceeding 95°F. Keep in a secure location out of the reach of children and pets. Keep the container tightly closed when not in use.
Exposure to extreme temperatures, light, or moisture can affect the integrity and effectiveness of medications. Always store medications properly (e.g., away from the bathroom, kitchen sink, or other damp places).
Side effects
As with all medications, side effects may occur. Potential side effects include, but are not limited to, diarrhea, nausea, vomiting, excessive gas, and stomach cramping. These effects may be more common at higher dosages.
Contact your veterinarian immediately if you notice your pet has irritation and/or bleeding in their mouth and throat.
Notify your veterinarian if your pet experiences any of the effects described above, or if you notice any other side effects that are persistent or troublesome.
If you notice anything unusual, please consult your veterinarian.
Precautions
Before using this product, please review the product label and full Prescribing Information for important safety information, including any relevant warnings and precautions.
For use in animals only. Keep out of reach of children and animals.
Discontinue use in animals with symptoms of sensitivity or allergy.
Do not inhale (or allow your animal to inhale) any powder from this medication, as it may cause respiratory irritation and worsen preexisting asthma. Crushing tablets should generally be avoided.
Pancrelipase can cause skin irritation; avoid contact with mucous membranes and skin. Wash your hands immediately after handling.
Do not administer pancrelipase products to animals with a known or suspected allergy/hypersensitivity to pork products. Individuals with severe pork allergies should not handle this product.
Do not administer this medication to animals with a known or suspected allergy/hypersensitivity to it or any of its ingredients. Allergic reactions to medications may occur. Please inform Vetsource and your veterinarian if your pet has any known sensitivities or allergies, especially to medications and supplements.
If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways; difficulty breathing; agitation; profuse salivation; and widespread hives or itching.
Drug and food interactions
The following drugs* may have potential interactions with this medication:
antacids (containing calcium and/or magnesium), folic acid, and iron-containing products (e.g., ferrous sulfate).
*NOTE: This may not be a comprehensive list. Contact your veterinarian if your pet experiences any unusual reactions when multiple medications and/or supplements are given together.
As with all medications, please consult your veterinarian if you have any questions or concerns prior to use. Please ensure your veterinarian is aware of all medications, supplements, and over-the-counter (OTC) products that your pet is currently using. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.
Adverse reactions
If you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer Neogen at 1-800-525-2022 or Vetsource Pet Owner Care at 877-738-4443.
Overdose
If you have any reason to suspect an overdose, call your doctor/veterinarian or the appropriate poison control resource immediately.
For humans:
The national toll-free Poison Help line, 1-800-222-1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories.
For animals:
The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888-426-4435.
Pet Poison Helpline® also provides a 24/7 animal poison control service at 855-764-7661.
*Please note: this information is for third-party services and is provided for convenience in case of potential poison-related emergencies. There may be consultation fee for these services.
Disclaimer
The content provided on this page is NOT medical advice.
All content, including the images and product description above, is intended for general informational purposes only and should not be considered a substitute for professional veterinary consultation, diagnosis, or treatment.
For additional information about this product and how it fits into your pet's individual treatment plan, please consult your veterinarian.
Last revised: 3/12/2026
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Description
Product detailsPancrePlus is a pancreatic enzyme concentrate of porcine origin. It is indicated for use as a digestive aid in replacement therapy where digestion of protein, carbohydrate, and fat is inadequate due to exocrine pancreatic insufficiency.This product is an oral tablet formulation (not powder).- Prescription tablets containing enzymes that aid in digestion for dogs and cats with Exocrine Pancreatic Insufficiency (EPI)
- Helps pets lacking the necessary enzymes digest proteins, carbohydrates, and fats from their meals
- Provides consistent digestive support that is easy to administer
- Available in both powder and tablet forms, with a palatable porcine base
- Made in the USA
Product sourced directly from the manufacturer or their approved distributor. Guaranteed genuine product backed by the manufacturer.ForDogs and CatsActive ingredient(s)Pancrelipase (Lipase, Protease, Amylase)Inactive ingredientsComplete inactive ingredients list not provided by manufacturer.Brand namePancrePlus TabletsDrug classPancreatic enzymesProduct flavoringThe manufacturer does not provide specific flavoring information for this product.**The pancreatic enzyme concentrate in this medication is derived from porcine (pork) sources. Consult your veterinarian before using this product if your pet has an allergy to pork products.ManufacturerNeogenProduct strength & sizeEach tablet contains a minimum of:Lipase 9,000 USP unitsProtease 57,000 USP unitsAmylase 64,000 USP unitsPlease ensure the selected product and quantity are appropriate for your pet, as recommended by your veterinarian. For current availability, please refer to the product selection above.UsageFor additional product information, please refer to the product label and the full Prescribing Information provided in the manufacturer’s package insert.PancrePlus Tablets should be administered as directed by your veterinarian. Wash your hands immediately after handling. Please consult your veterinarian before making any changes or discontinuing the prescribed dosing schedule.PancrePlus Tablets are not intended to be mixed directly with food. After administering a dose, follow immediately with food or water to reduce the risk of damage to the throat/esophagus.Manufacturer Dosage and Administration:PancrePlus Tablets should be administered before each meal. Your veterinarian will determine the appropriate dosage according to the severity of the condition and weight of the animal.Average dose/meal:Dogs: 2 - 3 tabletsCats: 1/2 - 1 tabletMissed dosesAdminister the dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not give more medication than prescribed or two doses at once.If you have questions about your pet’s prescribed dosing schedule (e.g., timing, interval), please consult your veterinarian.StorageStore in a cool, dry place at a controlled room temperature not exceeding 95°F. Keep in a secure location out of the reach of children and pets. Keep the container tightly closed when not in use.Exposure to extreme temperatures, light, or moisture can affect the integrity and effectiveness of medications. Always store medications properly (e.g., away from the bathroom, kitchen sink, or other damp places).Side effectsAs with all medications, side effects may occur. Potential side effects include, but are not limited to, diarrhea, nausea, vomiting, excessive gas, and stomach cramping. These effects may be more common at higher dosages.Contact your veterinarian immediately if you notice your pet has irritation and/or bleeding in their mouth and throat.Notify your veterinarian if your pet experiences any of the effects described above, or if you notice any other side effects that are persistent or troublesome.If you notice anything unusual, please consult your veterinarian.PrecautionsBefore using this product, please review the product label and full Prescribing Information for important safety information, including any relevant warnings and precautions.For use in animals only. Keep out of reach of children and animals.Discontinue use in animals with symptoms of sensitivity or allergy.Do not inhale (or allow your animal to inhale) any powder from this medication, as it may cause respiratory irritation and worsen preexisting asthma. Crushing tablets should generally be avoided.Pancrelipase can cause skin irritation; avoid contact with mucous membranes and skin. Wash your hands immediately after handling.Do not administer pancrelipase products to animals with a known or suspected allergy/hypersensitivity to pork products. Individuals with severe pork allergies should not handle this product.Do not administer this medication to animals with a known or suspected allergy/hypersensitivity to it or any of its ingredients. Allergic reactions to medications may occur. Please inform Vetsource and your veterinarian if your pet has any known sensitivities or allergies, especially to medications and supplements.If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways; difficulty breathing; agitation; profuse salivation; and widespread hives or itching.Drug and food interactionsThe following drugs* may have potential interactions with this medication: antacids (containing calcium and/or magnesium), folic acid, and iron-containing products (e.g., ferrous sulfate).*NOTE: This may not be a comprehensive list. Contact your veterinarian if your pet experiences any unusual reactions when multiple medications and/or supplements are given together.As with all medications, please consult your veterinarian if you have any questions or concerns prior to use. Please ensure your veterinarian is aware of all medications, supplements, and over-the-counter (OTC) products that your pet is currently using. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.Adverse reactionsIf you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer Neogen at 1-800-525-2022 or Vetsource Pet Owner Care at 877-738-4443.OverdoseIf you have any reason to suspect an overdose, call your doctor/veterinarian or the appropriate poison control resource immediately.For humans:The national toll-free Poison Help line, 1-800-222-1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories.For animals:The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888-426-4435.Pet Poison Helpline® also provides a 24/7 animal poison control service at 855-764-7661.*Please note: this information is for third-party services and is provided for convenience in case of potential poison-related emergencies. There may be consultation fee for these services.DisclaimerThe content provided on this page is NOT medical advice.All content, including the images and product description above, is intended for general informational purposes only and should not be considered a substitute for professional veterinary consultation, diagnosis, or treatment.For additional information about this product and how it fits into your pet's individual treatment plan, please consult your veterinarian.Last revised: 3/12/2026 -
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