PromAce (Acepromazine) Tablets

PromAce Tablets contain acepromazine, a rapid-acting phenothiazine sedative/tranquilizer used to help control excitability before minor procedures and stressful events.

Medications can play a significant role in comprehensive behavior modification therapy. Please follow your pet’s individual treatment plan, which may include a combination of medications and behavioral modification strategies, as recommended by your veterinarian or animal behaviorist.

Dogs, Cats, and Horses

Acepromazine maleate

Microcrystalline cellulose, corn starch, magnesium stearate, dextrose monohydrate.

PromAce Tablets

Phenothiazine sedative/tranquilizer

Boehringer Ingelheim

This product may be available in multiple strengths and/or sizes; please select the appropriate option for your pet as recommended by your veterinarian.

For current availability, please refer to the product selection above.

PromAce Tablets should be given orally as directed by your veterinarian. Please consult your veterinarian before making any changes to the prescribed dosing schedule.

Animals sedated with this medication may startle easily; whenever possible, treated animals should be kept in a quiet, safe environment.

Administer the dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not give two doses at once.

Store in a cool, dry place at a controlled room temperature (68 to 77°F, excursions permitted between 59 and 86°F). Keep in a tight, light-resistant container and out of the reach of children and pets. Store away from heat and direct sunlight. Do not store in the bathroom, near the kitchen sink, or in damp places. The medicine may break down if exposed to heat or moisture.

Medication effects, including sedative and/or side effects, may last up to 24 hours after administration. Individual response may vary from one pet to another.

This medication is generally well tolerated. Possible side effects include (but may not be limited to): drowsiness, mild respiratory distress (reverse sneezing), low blood pressure, constipation, urinary retention, and dry eyes/decreased tear production.

This medication may discolor your pet’s urine to a pink or red-brown color; this potential effect is not considered harmful and will resolve once the medication is eliminated from the body.

Contact your veterinarian immediately if your pet has very low blood pressure (leading to fainting or collapse) or displays extreme behavioral changes including aggression, biting/chewing, and/or nervousness.

Notify your veterinarian if your pet experiences any of the effects described above, or if you notice any other side effects that are persistent or troublesome.

If you notice anything unusual, please consult your veterinarian.

Labeled for use in dogs only.

Do NOT use in animals intended for human consumption.

This medication should NOT be used in animals exposed to any organophosphate agent or procaine hydrochloride (Novocaine). Some flea collars may contain an organophosphate ingredient; if your pet is currently using one of these collars, consult your veterinarian before starting this medication.

Use with caution in animals with preexisting liver dysfunction/impairment, heart disease, low blood pressure, dehydration, anemia, or leukopenia (low white blood cell count).

Safe use of this medication has not been established in breeding, pregnant, or lactating animals.

The sedative effects of acepromazine can be overridden by arousal or sudden startling. Combination therapy may be required, and treated pets should always be kept in a safe, quiet environment whenever possible to prevent this from occurring.

Do not administer to animals with a known history or suspected allergy/hypersensitivity to any phenothiazine drug, including this medication or any of its ingredients. Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies.

If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways, difficulty breathing, agitation, profuse salivation, and widespread hives or itching.

The following drugs* may have potential interactions with this medication: antacids (containing aluminum, calcium, and/or magnesium), antidiabetic agents (including insulins), antidiarrheals (e.g., bismuth subsalicylate, kaolin/pectin), azole antifungals (e.g., itraconazole, ketoconazole), beta blockers (e.g., atenolol, sotalol), blood pressure medications (e.g., amlodipine, enalapril, telmisartan), CNS depressant drugs (e.g., dexmedetomidine, hydroxyzine, opioids), epinephrine, metoclopramide, NSAIDs, organophosphate agents, pergolide, phenobarbital, phenylpropanolamine (Proin), procaine, selegiline, SSRIs (e.g., fluoxetine, sertraline), sucralfate, tramadol, and tricyclic antidepressants (e.g., amitriptyline, clomipramine).

*NOTE: this may not be a comprehensive list. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.

Please ensure your veterinarian is aware of all medications and supplements that your pet is currently receiving. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.

If you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer Boehringer Ingelheim Animal Health USA at 1-888-637-4251 or Vetsource Pet Owner Care at 877-738-4443.

If you have any reason to suspect an overdose, call your doctor/veterinarian or the appropriate poison control resource immediately.

For humans:

The national toll-free Poison Help line, 1-800-222-1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories.

For animals:

The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888-426-4435.

Pet Poison Helpline® also provides a 24/7 animal poison control service at 855-764-7661.

All content, including the images and product description above, is intended for general informational purposes only and should not be considered a substitute for professional veterinary consultation, diagnosis, or treatment.

Consult your veterinarian for complete information about this product and how it fits into your pet's individual treatment plan.