Product details
Silver Sulfadiazine Cream is a topical antimicrobial medication used to treat skin infections and burns. This product is a topical cream- not for ophthalmic use.
- Used to treat burns and topical (skin) infections in dogs, cats, and horses.
- Broad antimicrobial activity- effective against yeast and a variety of bacteria.
- Use with caution in animals with a sulfonamide (“sulfa“) drug allergy.
- May be prescribed for other animal species; please consult your veterinarian.
- While this drug does not have an FDA-approved indication for all animal uses, it is commonly accepted for veterinarians to prescribe this medication for use in animals.
*Please note: This is a generic medication. Product packaging and appearance, including size, color, and shape, may differ from the description or images provided and are subject to manufacturer availability.
Product sourced directly from the manufacturer or their approved distributor. Guaranteed genuine product backed by the manufacturer.
For
Dogs, Cats, and Horses
Active ingredient(s)
Silver sulfadiazine (1%)
Common brand names
Silvadene, SSD, Thermazene
Drug class
Sulfonamide antimicrobial, Topical
Product strength & size
This topical cream contains 10 mg of silver sulfadiazine per 1 gram of cream. Please ensure the selected product is appropriate for your pet, as recommended by your veterinarian.
For current availability, please refer to the product selection above.
Usage
Silver Sulfadiazine Cream should be applied topically as directed by your veterinarian.
Wash your hands thoroughly with soap and water after handling the medication. Please consult your veterinarian before making any changes or discontinuing the prescribed dosing schedule.
For general topical use:
Wear gloves and/or wash your hands thoroughly with soap and water before and after applying the medication.
Cleanse the affected area(s) prior to application as directed by your veterinarian.
Using a clean finger or sterile device (e.g., gauze pad, swab), apply the prescribed amount of cream to the affected area(s) as instructed.
To prevent contamination, do NOT allow the jar (or the medication inside) to touch any surface besides the clean finger or sterile device used for application.
Dressings may be applied over the cream. Do NOT allow your pet to lick or chew the application site(s) for at least 20 to 30 minutes.
Avoid sensitive areas; do NOT allow the medication to contact your pet’s eyes, nose, or mouth.
Complete the entire course of treatment as prescribed, even if your pet's condition has improved. Failure to complete the full treatment course may cause recurrence or worsening of the infection. Contact your veterinarian ahead of time if your pet needs a refill.
Missed doses
Administer the dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not apply two doses at once or more medication than prescribed.
Storage
Store in a cool, dry place at a controlled room temperature (68 to 77°F, excursions permitted between 59 and 86°F). Keep the container tightly sealed when not in use and out of the reach of children and pets. Store away from heat and direct sunlight. Do not store in the bathroom, near the kitchen sink, or in damp places. The medicine may break down if exposed to heat or moisture.
Side effects
Side effects are generally uncommon with this medication, especially when only applied to a small area. The most common side effects are redness or irritation at the application site.
Systemic side effects are considered unlikely with this topical medication. The risk of these effects is increased in animals with significant kidney or liver impairment, especially when this medication is used over a large area and/or for a prolonged period.
Contact your veterinarian immediately if your pet experiences eye dryness or shows any signs of an allergic/hypersensitivity reaction (e.g., swelling of the face and throat, noisy or labored breathing, severe rash).
Notify your veterinarian if your pet experiences any of the effects described above, or if you notice any other side effects that are persistent or troublesome.
If you notice anything unusual, please consult your veterinarian.
Precautions
Contact your veterinarian if your pet’s condition does not improve or worsens within 2 to 3 days after starting this medication.
Use with caution in animals with a sulfonamide (“sulfa“) drug allergy.
Animals with significant kidney or liver impairment may have an increased risk of adverse effects, especially when this medication is used over a large area and/or for a prolonged period.
Safe use of this medication has not been established in breeding, pregnant, or lactating animals. In humans, this medication is NOT used on pregnant women approaching or at term, on premature infants, or on newborn infants during the first 2 months of life. If your pet is in one of these groups, consult your veterinarian before using this medication.
Contact with any surface besides the clean finger or sterile device used for application may contaminate the product.
Do not administer to animals with a known history or suspected allergy/hypersensitivity to this medication or any of its ingredients. Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies.
If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways; difficulty breathing; agitation; profuse salivation; and widespread hives or itching.
Drug and food interactions
Topical medications are not typically absorbed into the body in the same manner as oral or injectable medications. There are no documented drug or food interactions with this medication in animals; however, interactions may still be possible.
Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.
Please ensure your veterinarian is aware of all medications and supplements that your pet is currently receiving. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.
Adverse reactions
If you are concerned that your pet has experienced an adverse reaction to this medication, please contact Vetsource Pet Owner Care at 877-738-4443.
Overdose
If you have any reason to suspect an overdose, call your doctor/veterinarian or the appropriate poison control resource immediately.
For humans:
The national toll-free Poison Help line, 1-800-222-1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories.
For animals:
The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888-426-4435.
Pet Poison Helpline® also provides a 24/7 animal poison control service at 855-764-7661.
*Please note: this information is for third-party services and is provided for convenience in case of potential poison-related emergencies. There may be consultation fee for these services.
Disclaimer
The content provided on this page is NOT medical advice.
All content, including the images and product description above, is intended for general informational purposes only and should not be considered a substitute for professional veterinary consultation, diagnosis, or treatment.
Consult your veterinarian for complete information about this product and how it fits into your pet's individual treatment plan.
Last revised: 7/07/2025
-
Description
Product detailsSilver Sulfadiazine Cream is a topical antimicrobial medication used to treat skin infections and burns. This product is a topical cream- not for ophthalmic use.- Used to treat burns and topical (skin) infections in dogs, cats, and horses.
- Broad antimicrobial activity- effective against yeast and a variety of bacteria.
- Use with caution in animals with a sulfonamide (“sulfa“) drug allergy.
- May be prescribed for other animal species; please consult your veterinarian.
- While this drug does not have an FDA-approved indication for all animal uses, it is commonly accepted for veterinarians to prescribe this medication for use in animals.
*Please note: This is a generic medication. Product packaging and appearance, including size, color, and shape, may differ from the description or images provided and are subject to manufacturer availability.Product sourced directly from the manufacturer or their approved distributor. Guaranteed genuine product backed by the manufacturer.ForDogs, Cats, and HorsesActive ingredient(s)Silver sulfadiazine (1%)Common brand namesSilvadene, SSD, ThermazeneDrug classSulfonamide antimicrobial, TopicalProduct strength & sizeThis topical cream contains 10 mg of silver sulfadiazine per 1 gram of cream. Please ensure the selected product is appropriate for your pet, as recommended by your veterinarian.For current availability, please refer to the product selection above.UsageSilver Sulfadiazine Cream should be applied topically as directed by your veterinarian.Wash your hands thoroughly with soap and water after handling the medication. Please consult your veterinarian before making any changes or discontinuing the prescribed dosing schedule.For general topical use:Wear gloves and/or wash your hands thoroughly with soap and water before and after applying the medication.Cleanse the affected area(s) prior to application as directed by your veterinarian.Using a clean finger or sterile device (e.g., gauze pad, swab), apply the prescribed amount of cream to the affected area(s) as instructed.To prevent contamination, do NOT allow the jar (or the medication inside) to touch any surface besides the clean finger or sterile device used for application.Dressings may be applied over the cream. Do NOT allow your pet to lick or chew the application site(s) for at least 20 to 30 minutes.Avoid sensitive areas; do NOT allow the medication to contact your pet’s eyes, nose, or mouth.Complete the entire course of treatment as prescribed, even if your pet's condition has improved. Failure to complete the full treatment course may cause recurrence or worsening of the infection. Contact your veterinarian ahead of time if your pet needs a refill.Missed dosesAdminister the dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not apply two doses at once or more medication than prescribed.StorageStore in a cool, dry place at a controlled room temperature (68 to 77°F, excursions permitted between 59 and 86°F). Keep the container tightly sealed when not in use and out of the reach of children and pets. Store away from heat and direct sunlight. Do not store in the bathroom, near the kitchen sink, or in damp places. The medicine may break down if exposed to heat or moisture.Side effectsSide effects are generally uncommon with this medication, especially when only applied to a small area. The most common side effects are redness or irritation at the application site.Systemic side effects are considered unlikely with this topical medication. The risk of these effects is increased in animals with significant kidney or liver impairment, especially when this medication is used over a large area and/or for a prolonged period.Contact your veterinarian immediately if your pet experiences eye dryness or shows any signs of an allergic/hypersensitivity reaction (e.g., swelling of the face and throat, noisy or labored breathing, severe rash).Notify your veterinarian if your pet experiences any of the effects described above, or if you notice any other side effects that are persistent or troublesome.If you notice anything unusual, please consult your veterinarian.PrecautionsContact your veterinarian if your pet’s condition does not improve or worsens within 2 to 3 days after starting this medication.Use with caution in animals with a sulfonamide (“sulfa“) drug allergy.Animals with significant kidney or liver impairment may have an increased risk of adverse effects, especially when this medication is used over a large area and/or for a prolonged period.Safe use of this medication has not been established in breeding, pregnant, or lactating animals. In humans, this medication is NOT used on pregnant women approaching or at term, on premature infants, or on newborn infants during the first 2 months of life. If your pet is in one of these groups, consult your veterinarian before using this medication.Contact with any surface besides the clean finger or sterile device used for application may contaminate the product.Do not administer to animals with a known history or suspected allergy/hypersensitivity to this medication or any of its ingredients. Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies.If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways; difficulty breathing; agitation; profuse salivation; and widespread hives or itching.Drug and food interactionsTopical medications are not typically absorbed into the body in the same manner as oral or injectable medications. There are no documented drug or food interactions with this medication in animals; however, interactions may still be possible.Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.Please ensure your veterinarian is aware of all medications and supplements that your pet is currently receiving. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.Adverse reactionsIf you are concerned that your pet has experienced an adverse reaction to this medication, please contact Vetsource Pet Owner Care at 877-738-4443.OverdoseIf you have any reason to suspect an overdose, call your doctor/veterinarian or the appropriate poison control resource immediately.For humans:The national toll-free Poison Help line, 1-800-222-1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories.For animals:The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888-426-4435.Pet Poison Helpline® also provides a 24/7 animal poison control service at 855-764-7661.*Please note: this information is for third-party services and is provided for convenience in case of potential poison-related emergencies. There may be consultation fee for these services.DisclaimerThe content provided on this page is NOT medical advice.All content, including the images and product description above, is intended for general informational purposes only and should not be considered a substitute for professional veterinary consultation, diagnosis, or treatment.Consult your veterinarian for complete information about this product and how it fits into your pet's individual treatment plan.Last revised: 7/07/2025 -
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