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Simparica TRIO Chewables for Dogs

This product requires a veterinary prescription.
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Simparica Trio® Chewables for Dogs
Product Information
Simparica Trio® is a pork liver-flavored chewable tablet administered once per month to protect your dog from heartworm disease, fleas, ticks, roundworms, and hookworms.
For
Dogs (8 weeks of age and older)
Generic Name
Sarolaner, Moxidectin, Pyrantel
Brand Name
Simparica Trio® Chewable Tablets
Drug Class
Isoxazoline Ectoparasiticide, Macrocyclic Lactone Antiparasitic, Antiparasitic
Product Flavoring
Simparica Trio® is a pork liver-flavored chewable tablet.
*Contains pork, soy, lactose, corn, and wheat.
Manufacturer
Zoetis
Benefits
  • One Chew, Triple Protection: Simparica Trio is the first FDA-approved monthly chewable that protects your dog against heartworm disease, ticks, fleas, roundworms, and hookworms. Approved for puppies as young as eight weeks old and weighing at least 2.8 pounds.
  • Heartworm Protection: Studies to support FDA-approval showed one dose provided 100% protection against heartworm disease.
  • FDA-Approved to Prevent Lyme Infections: Simparica Trio is the first FDA-approved product of its kind and the only one approved to prevent Lyme infections as a direct result of killing deer ticks. It’s proven to kill five types of ticks including the Gulf Coast Tick, Deer Tick, American Dog Tick, Lone Star Tick, Brown Dog Tick.
  • Kills Fleas & Intestinal Parasites: Prevents flea infestation by killing fleas before they can even lay eggs. Starts killing within 4 hours and achieved 100% effectiveness in 8 hours in a study. Treats roundworms and hookworms to protect your dog from intestinal parasites.
  • Satisfaction Guaranteed & Easy-to-Administer: Simparica Trio comes with a 100% satisfaction guarantee on prevention and is administered once a month with or without food. In a study 9 out of 10 dogs voluntarily consumed this tasty liver-flavored chew.
Active Ingredients
Sarolaner, Moxidectin, Pyrantel pamoate
Usage
*See enclosed insert for complete manufacturer dosage and administration recommendations*
Simparica Trio® should be given orally as directed by your veterinarian.
This medication can be given with or without food. Care should be taken to ensure that your dog consumes the complete dose, and that part of the dose is not lost or refused.
This medication should be administered to your dog year-round at monthly (every 30 day) intervals for continuous protection from heartworm disease, fleas, ticks, roundworms, and hookworms. For dogs over 132 lbs, administer the appropriate combination of tablets to ensure complete protection.
Remove only 1 tablet at a time from the foil-backed blister card and return the card to the box to protect from light. Tablets should remain sealed and only taken out of the blister pack at the time of dosing.
Missed Doses
Administer the dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not give two doses at once.
If your pet has missed a dose, please consult your veterinarian.
Side Effects
Simparica Trio is generally well tolerated in dogs, and there are very few side effects when given at the usual dosage. Reported side effects with this medication include (but may not be limited to): vomiting, diarrhea, lethargy, and loss of appetite.
Notify your veterinarian if the effects described above or any other side effects appear and become persistent or troublesome.
Other side effects may occur. If you notice anything unusual, contact your veterinarian.
Drug & Food Interactions
There are no documented drug or food interactions with Simparica Trio.
Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.
Please ensure your veterinarian is aware of all medications and supplements that your pet is currently receiving. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosage(s) or monitor your pet more closely.
Cautions
*See product packaging/insert for complete product details including warnings and precautions.
For oral use in dogs only- not for use in humans.
Sarolaner is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders.
The safe use of Simparica Trio has not been evaluated in breeding, pregnant, or lactating dogs.
Do not administer to animals with known history or suspected allergy/hypersensitivity to this medication or any of its ingredients. Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies.
If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways, difficulty breathing, agitation, profuse salivation, and widespread hives or itching.
Adverse Reactions
If you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer Zoetis at 888-963-8471 or Vetsource customer service at 877-738-4443.
Storage
Store in a cool, dry place at a controlled room temperature (at or below 86°F). Keep this medication in its original packaging and out of the reach of children and pets. Store away from heat and direct sunlight. Do not store this medication in the bathroom, near the kitchen sink, or in damp places. The medicine may break down if exposed to heat or moisture.
Sourced directly from the manufacturer or their approved distributor. Guaranteed genuine product backed by the manufacturer.

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