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Simparica TRIO Chewables for Dogs

This product requires a veterinary prescription.
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Simparica Trio® Chewables for Dogs
Product Information
Simparica Trio®  Chewable Tablets are pork flavored chewable tablets administered once a month to protect your dog from heartworms, fleas, ticks, and intestinal parasites.
For
Dogs 
Generic Name
Sarolaner, Moxidectin, Pyrantel
Brand Name 
Simparica Trio®  Chewable Tablets
Drug Class
Isoxazoline Ectoparasiticide, Macrocyclic Lactone Antiparasitic, Antiparasitic
Product Flavoring
Simparica Trio® is a pork flavored chewable tablet.
*Contains pork, soy, lactose, corn, and wheat.
Manufacturer
Zoetis
Product Description & Form
Simparica Trio® 2.8-5.5 lbs: 8.5 mm, reddish brown, pentagon (5 sided) shaped rounded edges, no score, imprinted with 3. (NDC 54771-2667-03)
Simparica Trio® 5.6-11 lbs: 10.7 mm, reddish brown, pentagon (5 sided) shaped rounded edges, no score, imprinted with 6. (NDC 54771-2684-03)
Simparica Trio® 11.1-22 lbs: 13.73 mm, reddish brown, pentagon (5 sided) shaped rounded edges, no score, imprinted with 12. (NDC 54771-2668-03)
Simparica Trio® 22.1-44 lbs: 17 mm, reddish brown, pentagon (5 sided) shaped rounded edges, no score, imprinted with 24. (NDC 54771-2669-03)
Simparica Trio® 44.1-88 lbs: 20 mm, reddish brown, pentagon (5 sided) shaped rounded edges, no score, imprinted with 48. (NDC 54771-2670-03)
Simparica Trio® 88.1-132 lbs: 24 mm, reddish brown, pentagon (5 sided) shaped rounded edges, no score, imprinted with 72. (NDC 54771-2671-03)
Benefits
  • Once a month pork flavored chewable tablet that is highly palatable
  • Prevents heartworm disease cause by D. immitis when given routinely on a monthly basis
  • Kills adult fleas and treats flea infestations from C. felis when given routinely on a monthly basis
  • Treats and controls tick infestations from the Lone Star tick (A. americanum), Gulf Coast tick (A. maculatum), American Dog tick (D. variabilis), Black-Legged (Deer) ticks (I. scapularis), and Brown Dog ticks (R. sanguineus) when given routinely on a monthly basis
  • Treats and controls infections from roundworms and adult hookworms when given routinely on a monthly basis
  • Starts killing fleas in 4 hours
  • Kills 94.2% of ticks within 48 hours
  • Shown to kill existing deer tick infestations within 8 hours. Lyme disease is typically transmitted in 24-48 hours
  • Approved for dogs 8+ weeks of age, weighing more than 2.8 lbs
Active Ingredients
Sarolaner, Moxidectin, Pyrantel pamoate
Usage
Simparica Trio® should be given orally as directed by your veterinarian. This medication should be administered at monthly (every 30 day) intervals, year-round to guarantee protection from heartworms, fleas, ticks, and intestinal parasites in dogs.
Remove only 1 tablet at a time from the foil-backed blister card and return the card to the box to protect from light.  Do not remove tablet from foil wrapper until you are ready to give it to your pet. Offer to the pet as a treat by hand or in a small amount of food. Make sure entire tablet is consumed.  
Missed Doses
Give the dose as soon as you remember, unless it is time for the next dose.  Do not double dose.  If your pet has missed a dose please consult with your veterinarian. 
Side Effects
Simparica Trio®  is generally well tolerated in dogs. There are very few side effects when the drug is given at the usual dose. The following side effects have been reported with the use of  Simparica Trio® : vomiting, diarrhea, lethargy, and inappetance. If this occurs, notify your veterinarian. 
Use with caution in dogs with a history of seizures.
Other side effects may occur. If you notice anything unusual, contact your veterinarian.
Drug & Food Interactions
There are no documented drug interactions with Simparica Trio®. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together. Make sure to tell your veterinarian what other medication you are giving to your pet. Quite often your veterinarian may prescribe two different medications, and a drug interaction may be anticipated. In this case, your veterinarian may vary the dose and/or monitor your pet more closely.
Cautions
Safe use of Simparica Trio®  in breeding, pregnant, or lactating dogs has not been evaluated.
Use with caution in dogs with a history of seizures.
Allergic reactions to medications may occur. Be sure to inform VetSource and your veterinarian if your pet has any known drug sensitivities or allergies. If your pet displays symptoms of an allergic reaction, call your veterinarian immediately or go to a veterinary emergency clinic. Symptoms may include but are not limited to: swollen lips, tongue, face, airways; difficulty breathing; agitation; profuse salivation; vomiting; widespread hives and itching.
Adverse Reaction
If you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer Zoetis at 888-963-8471 or contact Vetsource customer service at 877-738-4443.
Storage
Store long term at or below 86° F.  Store in original packaging to protect from light.  Keep out of reach of children and pets. Store in a childproof container. Store this medicine in a cool, dry place at room temperature. Store away from heat and direct sunlight. Do not store this medicine in the bathroom, near the kitchen sink or in damp places. The medicine may break down if exposed to heat or moisture.
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