Product details
Ursodiol is a naturally occurring bile acid used to treat certain liver and gallbladder conditions in animals, including cholestasis (blocked or slowed bile flow) and biliary sludge.
This product is a tablet formulation.
- Used to treat various liver and gallbladder conditions in dogs and cats, including chronic liver and/or bile duct inflammation.
- Helps to restore healthy liver function, reduce symptoms, and slow chronic disease progression.
- Do not use this medication in certain species, including rabbits, guinea pigs, and rodents, as liver toxicity may occur.
- May be prescribed for other animal species; please consult your veterinarian.
- While this drug does not have an FDA-approved indication for all animal uses, it is commonly accepted for veterinarians to prescribe this medication for use in animals.
*Please note: This is a generic medication. Product packaging and appearance, including size, color, and shape, may differ from the description or images provided and are subject to manufacturer availability.
Product sourced directly from the manufacturer or their approved distributor. Guaranteed genuine product backed by the manufacturer.
For
Dogs and Cats
Active ingredient(s)
Ursodiol
Common brand names
Urso 250, Urso Forte
Drug class
Bile acid, Gallstone solubilizing agent
Product strength & size
Ursodiol tablets may be available in multiple strengths and/or sizes. Please ensure the selected product and package size are appropriate for your pet, as recommended by your veterinarian.
For current availability, please refer to the product selection above.
Usage
Ursodiol Tablets should be given orally as directed by your veterinarian. Please consult your veterinarian before making any changes or discontinuing the prescribed dosing schedule.
This medication works best when given with food, which may also help reduce GI side effects (e.g., nausea) and mask its bitter taste.
Missed doses
Administer the dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not give two doses at once.
Storage
Store in a cool, dry place at a controlled room temperature (68 to 77°F, excursions permitted between 59 and 86°F). Keep in a tight, light-resistant container and out of the reach of children and pets. Store away from heat and direct sunlight. Do not store in the bathroom, near the kitchen sink, or in damp places. The medicine may break down if exposed to heat or moisture.
Side effects
Ursodiol is usually well-tolerated in dogs and cats. The most common side effects are diarrhea, nausea, and vomiting. Giving this medication with food may help decrease or prevent these effects.
Contact your veterinarian immediately if your pet experiences severe vomiting; lowered energy level or weakness; or yellowing of the skin, whites of the eyes, and/or gums.
Notify your veterinarian if your pet experiences any of the effects described above, or if you notice any other side effects that are persistent or troublesome.
If you notice anything unusual, please consult your veterinarian.
Precautions
This medication should NOT be administered this medication to certain species, including rabbits, guinea pigs, and rodents. These animals metabolize the medication differently, which results in the formation of a toxic substance that can cause serious liver damage and toxicity.
Do NOT administer this medication to animals with complete bile duct blockage, or those with a rare liver condition called vanishing bile duct syndrome.
Use with caution in animals with certain liver conditions (e.g., cholangitis, cholangiohepatitis) or complications related to gallstones.
Safe use of this medication has not been established in breeding, pregnant, or lactating animals. Discuss the risks of using this medication with your veterinarian if your pet is in one of these groups.
Do not administer to animals with a known history or suspected allergy/hypersensitivity to this medication or any of its ingredients. Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies.
If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways; difficulty breathing; agitation; profuse salivation; and widespread hives or itching.
Drug and food interactions
The following drugs* may have potential interactions with this medication: aluminum-containing antacids, cholestyramine, estrogens, fluoroquinolone antibiotics (e.g., ciprofloxacin), and sucralfate.
*NOTE: this may not be a comprehensive list. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.
Please ensure your veterinarian is aware of all medications and supplements that your pet is currently receiving. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.
Adverse reactions
If you are concerned that your pet has experienced an adverse reaction to this medication, please contact Vetsource Pet Owner Care at 877-738-4443.
Overdose
If you have any reason to suspect an overdose, call your doctor/veterinarian or the appropriate poison control resource immediately.
For humans:
The national toll-free Poison Help line, 1-800-222-1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories.
For animals:
The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888-426-4435.
Pet Poison Helpline® also provides a 24/7 animal poison control service at 855-764-7661.
*Please note: this information is for third-party services and is provided for convenience in case of potential poison-related emergencies. There may be consultation fee for these services.
Disclaimer
The content provided on this page is NOT medical advice.
All content, including the images and product description above, is intended for general informational purposes only and should not be considered a substitute for professional veterinary consultation, diagnosis, or treatment.
Consult your veterinarian for complete information about this product and how it fits into your pet's individual treatment plan.
Last revised: 7/17/2025
-
Description
Product detailsUrsodiol is a naturally occurring bile acid used to treat certain liver and gallbladder conditions in animals, including cholestasis (blocked or slowed bile flow) and biliary sludge. This product is a tablet formulation.- Used to treat various liver and gallbladder conditions in dogs and cats, including chronic liver and/or bile duct inflammation.
- Helps to restore healthy liver function, reduce symptoms, and slow chronic disease progression.
- Do not use this medication in certain species, including rabbits, guinea pigs, and rodents, as liver toxicity may occur.
- May be prescribed for other animal species; please consult your veterinarian.
- While this drug does not have an FDA-approved indication for all animal uses, it is commonly accepted for veterinarians to prescribe this medication for use in animals.
*Please note: This is a generic medication. Product packaging and appearance, including size, color, and shape, may differ from the description or images provided and are subject to manufacturer availability.Product sourced directly from the manufacturer or their approved distributor. Guaranteed genuine product backed by the manufacturer.ForDogs and CatsActive ingredient(s)UrsodiolCommon brand namesUrso 250, Urso ForteDrug classBile acid, Gallstone solubilizing agentProduct strength & sizeUrsodiol tablets may be available in multiple strengths and/or sizes. Please ensure the selected product and package size are appropriate for your pet, as recommended by your veterinarian.For current availability, please refer to the product selection above.UsageUrsodiol Tablets should be given orally as directed by your veterinarian. Please consult your veterinarian before making any changes or discontinuing the prescribed dosing schedule.This medication works best when given with food, which may also help reduce GI side effects (e.g., nausea) and mask its bitter taste.Missed dosesAdminister the dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not give two doses at once.StorageStore in a cool, dry place at a controlled room temperature (68 to 77°F, excursions permitted between 59 and 86°F). Keep in a tight, light-resistant container and out of the reach of children and pets. Store away from heat and direct sunlight. Do not store in the bathroom, near the kitchen sink, or in damp places. The medicine may break down if exposed to heat or moisture.Side effectsUrsodiol is usually well-tolerated in dogs and cats. The most common side effects are diarrhea, nausea, and vomiting. Giving this medication with food may help decrease or prevent these effects.Contact your veterinarian immediately if your pet experiences severe vomiting; lowered energy level or weakness; or yellowing of the skin, whites of the eyes, and/or gums.Notify your veterinarian if your pet experiences any of the effects described above, or if you notice any other side effects that are persistent or troublesome.If you notice anything unusual, please consult your veterinarian.PrecautionsThis medication should NOT be administered this medication to certain species, including rabbits, guinea pigs, and rodents. These animals metabolize the medication differently, which results in the formation of a toxic substance that can cause serious liver damage and toxicity.Do NOT administer this medication to animals with complete bile duct blockage, or those with a rare liver condition called vanishing bile duct syndrome.Use with caution in animals with certain liver conditions (e.g., cholangitis, cholangiohepatitis) or complications related to gallstones.Safe use of this medication has not been established in breeding, pregnant, or lactating animals. Discuss the risks of using this medication with your veterinarian if your pet is in one of these groups.Do not administer to animals with a known history or suspected allergy/hypersensitivity to this medication or any of its ingredients. Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies.If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways; difficulty breathing; agitation; profuse salivation; and widespread hives or itching.Drug and food interactionsThe following drugs* may have potential interactions with this medication: aluminum-containing antacids, cholestyramine, estrogens, fluoroquinolone antibiotics (e.g., ciprofloxacin), and sucralfate.*NOTE: this may not be a comprehensive list. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.Please ensure your veterinarian is aware of all medications and supplements that your pet is currently receiving. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.Adverse reactionsIf you are concerned that your pet has experienced an adverse reaction to this medication, please contact Vetsource Pet Owner Care at 877-738-4443.OverdoseIf you have any reason to suspect an overdose, call your doctor/veterinarian or the appropriate poison control resource immediately.For humans:The national toll-free Poison Help line, 1-800-222-1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories.For animals:The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888-426-4435.Pet Poison Helpline® also provides a 24/7 animal poison control service at 855-764-7661.*Please note: this information is for third-party services and is provided for convenience in case of potential poison-related emergencies. There may be consultation fee for these services.DisclaimerThe content provided on this page is NOT medical advice.All content, including the images and product description above, is intended for general informational purposes only and should not be considered a substitute for professional veterinary consultation, diagnosis, or treatment.Consult your veterinarian for complete information about this product and how it fits into your pet's individual treatment plan.Last revised: 7/17/2025 -
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