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Lutalyse Injection

This product requires a veterinary prescription.
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Lutalyse® Injection
Product Information
Lutalyse® Injection is a sterile solution that has a luteolytic effect in mares which can be used to synchronize estrus. 
Generic Name
Brand Names
Drug Class
Product Description & Form
Lutalyse® 5 mg/ml Injection 30 ml: clear, colorless solution. (NDC 54771-1327-01)
  • The luteolytic action can be utilized to alter the estrus cycle to better fit  breeding and management practices, to terminate pregnancies resulting from mismatings, and to treat certain conditions associated with prolonged luteal function
  • An entirely natural prostaglandin
  • For intramuscular use in cattle, swine and mares. 
  • Each mL contains dinoprost tromethamine equivalent to 5 mg dinoprost
Active Ingredients
Dinoprost tromethamine 
Inactive Ingredients
Water for injection, benzyl alcohol
Lutalyse® Injection should be given to your horse as directed by your veterinarian. Administered Intramuscularly only. Do not use the intravenous route. Wear gloves when preparing and administering this medication.  Use aseptic techniques when withdrawing each dose to decrease the possibility of post-injection bacterial infections. Adequately clean and disinfect the stopper prior to entry with a sterile needle and syringe. Injectable medications require needles and syringes.  Those items are purchased separately.  Please ask your veterinarian for a recommendation for the correct needle/syringe sizes for your pet. Use only sterile needles/syringes and use each needle/syringe only once. Dispose the needle/syringe immediately in a proper sharps disposal container. Sharps containers are sold separately.
The vial stopper may only be punctured by a needle up to 20 times. Use the contents of the vial within 12 weeks of first puncture, discard unused portion.
Note: Women of childbearing age, asthmatics, and persons with bronchial and other respiratory problems should exercise extreme caution when handling this product. In the early stages, women may be unaware of their pregnancies. 
Missed Doses
Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give 2 doses at once.
Side Effects
The manufacturer does not list any adverse effects for this product when used as labeled in livestock and horses has a wide margin of safety.  If used after the 5th month of gestation, increased risk of dystocia and decreased efficacy occur. Unknown side effects may occur. If you notice anything unusual, contact your veterinarian.
Drug & Food Interactions
Do not use non-steroidal medications at the same time this product is being administered. There are no documented interactions with this medication. Contact your veterinarian if your horse experiences any unusual reactions when different medications are given together.
Make sure to tell your veterinarian what other medication you are giving to your horse. Quite often your veterinarian may prescribe two different medications, and a drug interaction may be anticipated. In this case, your veterinarian may vary the dose and/or monitor your horse more closely.  Contact your veterinarian if your horse experiences any unusual reactions when different medications are given together.
Lutalyse® is readily absorbed through the skin and may cause abortion and/or bronchospasms; direct contact with the skin should therefore be avoided. Accidental spillage on the skin should be washed off immediately with soap and water. Wear gloves when handling.
Allergic reactions to medications may occur. Be sure to inform VetSource and your veterinarian if your horse has any known drug sensitivities or allergies. If your horse displays symptoms of an allergic reaction, call your veterinarian immediately or go to a veterinary emergency clinic. Symptoms may include but are not limited to: swollen lips, tongue, face, airways; difficulty breathing; agitation; profuse salivation; widespread hives and itching.
Adverse Reactions
If you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer Zoetis at 888-963-8471 or Vetsource customer service at 877-738-4443.
Store at 68°F to 77°F in controlled room temperature. Protect from freezing. Keep this medicine out of reach of children. Store in a childproof container. Store this medicine in a cool, dry place at room temperature. Store away from heat and direct sunlight. Do not store this medicine in the bathroom, near the kitchen sink or in damp places. The medicine may break down if exposed to heat or moisture.
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Nutritional Info