Product details
Methimazole is an antithyroid medication that inhibits the production of thyroid hormones and is commonly used to treat hyperthyroidism in cats.
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Methimazole has an FDA-approved indication for the treatment of hyperthyroidism in cats.
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This medication does not cure hyperthyroidism, but it may be prescribed for lifelong treatment.
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Side effects of this medication typically resolve over time, and most cats that tolerate this medication respond well to treatment.
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Generic methimazole tablets are not coated.
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Most often used in cats, but may be prescribed for other animal species. Please consult your veterinarian.
While this medication does not have an FDA-approved indication across all animal species, it is a common and acceptable practice for veterinarians to prescribe this human generic medication for use in animals.
*Please note: this is a generic medication. Product packaging and appearance, including size, color, and shape, may differ from the description or images provided and are subject to manufacturer availability.
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For
Cats
Active ingredient(s)
Methimazole
Common brand names
Felimazole®, Tapazole®
Drug class
Antithyroid agent
Product strength & size
This product is available in multiple strengths and sizes; please select the appropriate option for your pet as recommended by your veterinarian.
For current availability, please refer to the product selection above.
Usage
Methimazole should be given orally as directed by your veterinarian.
If you are pregnant, planning, or breastfeeding: wear gloves before handling this medication. All pet owners should wash their hands with soap and water after handling the medication or if contact is made with the litter or bodily fluids of a treated cat (even if gloves are worn).
Please consult your veterinarian before making any changes or discontinuing the prescribed dosing schedule. Your veterinarian will monitor your pet’s bloodwork while taking this medication.
This medication can be given with or without food, though your veterinarian may recommend giving it with food due to its bitter taste. If your pet vomits or appears unwell after receiving a dose on an empty stomach, give future doses with food or a small treat. If vomiting continues, contact your veterinarian.
Missed doses
Administer the dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not give two doses at once.
Storage
Store in a cool, dry place at a controlled room temperature (68 to 77°F, excursions permitted between 59 and 86°F). Keep in a tight, light-resistant container and out of the reach of children and pets. Store away from heat and direct sunlight. Do not store in the bathroom, near the kitchen sink, or in damp places. The medicine may break down if exposed to heat or moisture.
Side effects
Side effects may include (but are not limited to): vomiting, decreased appetite, and lethargy. These effects usually occur at the start of treatment and decrease over time.
Contact your veterinarian immediately if you notice your pet has unusual bruising, severe weakness, or facial itching/sores.
Notify your veterinarian if your pet experiences any of the effects described above, or if you notice any other side effects that are persistent or troublesome.
If you notice anything unusual, please consult your veterinarian.
Precautions
Do NOT use this medication in cats with liver disease, kidney failure, autoimmune diseases, or blood disorders (e.g., anemia, low white blood cells, etc.). “Live” vaccines should NOT be administered while your pet is being treated with methimazole.
Do NOT use this medication in breeding, pregnant, or lactating animals.
Do not administer to animals with a known history or suspected allergy/hypersensitivity to carbimazole, polyethylene glycol, or this medication and any of its ingredients. Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies.
If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways, difficulty breathing, agitation, profuse salivation, and widespread hives or itching.
Human exposure warning
This medication may represent a hazard to males or females who are actively trying to conceive, women who are pregnant or may become pregnant, and women who are breastfeeding. Unopened, intact tablets and capsules may not pose the same degree of risk as injectable drugs, which usually require extensive preparation. Cutting, crushing, or otherwise manipulating tablets and capsules will increase the risk of exposure. Wear gloves while handling this medication. Wash your hands thoroughly with soap and water after handling this medication.
Drug and food interactions
The following drugs* may have potential interactions with this medication: anticoagulants (e.g., warfarin), beta blockers (e.g., atenolol), benzimidazole antiparasitics (e.g., fenbendazole), digoxin, theophylline, and phenobarbital.
*NOTE: this may not be a comprehensive list. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.
Please ensure your veterinarian is aware of all medications and supplements that your pet is currently receiving. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.
Adverse reactions
If you are concerned that your pet has experienced an adverse reaction to this medication, please contact Vetsource Pet Owner Care at 877-738-4443.
Last revised: 4/11/2025