NexGard PLUS for Dogs

NexGard PLUS (afoxolaner, moxidectin, and pyrantel chewable tablets) chews deliver next-level protection all in one tasty soft chew. The one-and-done monthly beef flavored NexGard PLUS chews provide protection against fleas, ticks, heartworm disease, roundworms, and hookworms. NexGard PLUS chews are safe and approved for puppies as young as 8 weeks old, weighing 4 pounds or more.

From the maker of veterinarian-recommended HEARTGARD Plus (ivermectin/pyrantel)¹ chews, tasty NexGard PLUS chewables provide convenient, monthly parasite protection for the dog you love. Use with caution in dogs with a history of seizures or neurological disorders.

Dogs need parasite protection year-round. NexGard PLUS chews are designed for monthly dosing that’s a delight for your dog month after month.

Fleas pose an ever-present risk for dogs in many parts of the country. While the risk of flea infestations may be higher during warmer months, they can occur at any point throughout the year. NexGard PLUS chewables kill adult fleas fast, before they can lay eggs, for a full month. NexGard PLUS chewables are also approved to kill five species of ticks – including the four species that are most commonly found on dogs in the US.²

Heartworm disease is a serious condition that can cause permanent damage – and just one bite from an infected mosquito could put your pet at risk for this potentially deadly disease. Cases of heartworm disease have been reported in all 50 states – in both indoor and outdoor pets.³ The American Heartworm Society recommends that all pets receive heartworm disease prevention year-round. Ask your veterinarian about heartworm disease prevention for dogs with monthly NexGard PLUS chewables. All dogs should be tested for heartworms prior to starting a heartworm disease preventive.

With NexGard PLUS chewables, you’re protecting your dog from fleas and ticks, PLUS heartworm disease, 3 species of hookworms, and 2 species of roundworms – all with the tasty beef-flavored chew that’s designed for monthly dosing that’s a delight for your dogs.

References:

1. Data on file at Boehringer Ingelheim

2. Saleh MN, Sundstrom KD, Duncan KT, et al. Show us your ticks: a survey of ticks infesting dogs and cats across the USA. Parasites & Vectors. 2019;12(595).

3. Heartworm Parasite Prevalence Maps. Companion Animal Parasite Council. Accessed May 22, 2023.

Dogs (8 weeks of age and older)

Afoxolaner, Moxidectin, Pyrantel pamoate

Complete inactive ingredients list not provided by manufacturer.

NexGard PLUS

Isoxazoline ectoparasiticide, Macrocyclic lactone antiparasitic, Tetrahydropyrimidine anthelmintic

NexGard PLUS chewable tablets are beef flavored.

Boehringer Ingelheim Animal Health USA

*For dogs over 132 lbs., administer the appropriate combination of chewable tablets to cover your pet’s body weight.

NexGard PLUS should be given orally as directed by your veterinarian.

NexGard PLUS chews can be administered with or without food. Care should be taken to ensure that your dog consumes the complete dose, and that part of the dose is not lost or refused.

This medication should be administered to your dog year-round at monthly (every 30 day) intervals for continuous protection from heartworm disease, fleas, ticks, roundworms, and hookworms. For dogs over 132 lbs., administer the appropriate combination of tablets to ensure complete protection.

For heartworm disease prevention, NexGard PLUS should be given once monthly for at least six months after the dog’s last exposure to mosquitoes.

Remove only 1 tablet at a time from the foil-backed blister card and return the card to the box to protect from light. Tablets should remain sealed and only taken out of the blister pack at the time of dosing.

If a dose is missed: give NexGard PLUS immediately to resume monthly dosing and consult your veterinarian. Do not give two doses at once.

If multiple doses have been missed, consult your veterinarian prior to restarting the monthly dosing schedule.

Store in a cool, dry place at a controlled room temperature (at or below 77°F, with excursions permitted up to 104°F). Keep this medication in its original packaging and out of the reach of children and pets. Store away from heat and direct sunlight. Do not store in the bathroom, near the kitchen sink, or in damp places. The medicine may break down if exposed to heat or moisture.

NexGard PLUS is generally well tolerated, and side effects are uncommon when given at the usual dosage. The most frequently reported side effects include diarrhea, vomiting, lethargy, and itching.

Use with caution in dogs with a history of seizures or neurologic disorders. Contact your veterinarian immediately if your pet has a seizure after taking this medication.

Notify your veterinarian if your pet experiences any of the effects described above, or if you notice any other side effects that are persistent or troublesome.

If you notice anything unusual, please consult your veterinarian.

For oral use in dogs only- not for use in humans. Keep this and all drugs in a secure location out of the reach of children and animals to prevent accidental ingestion or overdose.

Afoxolaner, one of the ingredients in NexGard PLUS, is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders.

Treatment with fewer than six monthly doses after the last exposure to mosquitoes has not been fully evaluated and may not provide complete heartworm prevention. Prior to administration of NexGard PLUS chews, dogs should be tested for existing heartworm infection. At the discretion of the veterinarian, infected dogs should be treated with an adulticide to remove adult heartworms. NexGard PLUS chews are not effective against adult D. immitis.

The safe use of NexGard PLUS in breeding, pregnant, or lactating dogs has not been evaluated.

Do not administer to animals with a known history or suspected allergy/hypersensitivity to this medication or any of its ingredients. Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies.

If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways, difficulty breathing, agitation, profuse salivation, and widespread hives or itching.

There are no documented drug or food interactions with NexGard PLUS.

Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.

Please ensure your veterinarian is aware of all medications and supplements that your pet is currently receiving. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.

If you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer Boehringer Ingelheim Animal Health USA at 1-888-637-4251 or Vetsource Pet Owner Care at 877-738-4443.

If you have any reason to suspect an overdose, call your doctor/veterinarian or the appropriate poison control resource immediately.

For humans:

The national toll-free Poison Help line, 1-800-222-1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories.

For animals:

The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888-426-4435.

Pet Poison Helpline® also provides a 24/7 animal poison control service at 855-764-7661.

All content, including the images and product description above, is intended for general informational purposes only and should not be considered a substitute for professional veterinary consultation, diagnosis, or treatment.

Consult your veterinarian for complete information about this product and how it fits into your pet's individual treatment plan.