Name: Palladia Tablets
Brand: Zoetis
Availability: InStock

Product Information

Description

Product

Palladia® Tablets

Product Information

Palladia® Tablets are used for the treatment of Patnaik grade II or III, recurrent, cutaneous mast cell tumors (MCTs) with or without regional lymph node involvement in dogs.

For

Dogs

Generic Name

Toceranib

Brand Names

Palladia®

Drug Class

Tyrosine Kinase Inhibitor Antineoplastic

Manufacturer

Zoetis

Product Description & Form

Palladia® 10 mg 30 ct: 7mm, blue, round tablet, not scored, imprinted with TKI;10;Pfizer. (NDC 54771-1690-1)

Palladia® 15 mg 30 ct: 8mm, orange, round tablet, not scored, imprinted with TKI;15;Pfizer. (NDC 54771-1691-1)

Palladia® 50 mg 30 ct: 12mm, red, round tablet, not scored, imprinted with TKI;50;Pfizer. (NDC 54771-1692-1)

Benefits

FDA-approved medication for grades II or III canine mast cell tumors in dogs
Works by cutting off blood supply to the tumor and killing tumor cells

Active Ingredients

Toceranib phosphate

Usage

Palladia® should be given orally as directed by your veterinarian. Give dose immediately after removing from the bottle. May be given with or without food. May be hidden in treats, be certain your dog swallows the entire tablet(s). Do not crush or split tablets, it will disrupt the protective film coating. Wear gloves when handling medication and wash hands thoroughly with soap and water after handling.

Stop Palladia® immediately and contact your veterinarian if you notice any of the following changes in your dog: refusal to eat, vomiting or watery stools (especially if more frequent than twice in 24 hours), black tarry stools, bright red blood in vomit or stool, unexplained bruising or bleeding, or if your dog experiences other changes that concern you.

Missed Doses

Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give 2 doses at once.

Side Effects

Side effects may include diarrhea, anorexia, lethargy, vomiting, lameness, weight loss, blood in stool, GI bleeding, dehydration, and itchiness. If these effects continue and become troublesome, contact your veterinarian. Other side effects may occur. If you notice anything unusual, contact your veterinarian.

The presence of systemic mast cell tumor prior to treatment may predispose a dog to clinically significant mast cell degranulation with possible severe systemic adverse reactions when treated with Palladia®. Attempts should be made to rule out systemic mastocytosis prior to initiation of treatment with Palladia®.

Drug & Food Interactions

The following lists examples of medicines that can potentially interact with Palladia®: calcitriol, doxorubicin, fluconazole, itraconazole, lomustine, ketoconazole, NSAIDs, and vinblastine. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.

Make sure to tell your veterinarian what other medication you are giving to your pet. Quite often your veterinarian may prescribe two different medications, and a drug interaction may be anticipated. In this case, your veterinarian may vary the dose and/or monitor your pet more closely.

Cautions

Palladia® is for use in dogs only. Do not use in dogs used for breeding, or for pregnant or lactating. Children should not come in contact with Palladia®. Keep children away from feces, urine, or vomit of treated dogs.

To avoid exposure to drug, wash hands with soap and water after administering Palladia® and wear protective gloves to prevent direct contact with feces, urine, vomit, and broken or moistened Palladia® tablets. Place all waste materials in a plastic bag and seal before

general disposal. Do not wash any items soiled with stool, urine, or vomit from your dog with regular laundry. If eyes are accidentally exposed to the drug, rinse eyes with water immediately. In case of accidental ingestion by a person, seek medical advice immediately, show the package insert or label to the physician. Gastrointestinal discomfort such as vomiting or diarrhea may occur if this drug is accidentally ingested.

Pregnant women, women who may become pregnant, or nursing mothers should pay special attention to these handling precautions. Palladia®, like other drugs in its class, prevents the formation of new blood vessels in tumors. In a similar manner, Palladia® may affect blood vessel formation in the developing fetus and may harm an unborn baby (cause birth defects). For pregnant women, accidental ingestion of Palladia® may have adverse effects on pregnancy.

Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies. If your pet displays symptoms of an allergic reaction, call your veterinarian immediately or go to a veterinary emergency clinic. Symptoms may include but are not limited to: swollen lips, tongue, face, airways; difficulty breathing; agitation; profuse salivation; widespread hives and itching.

Adverse Reactions

If you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer Zoetis at 888-963-8471 or Vetsource customer service at 877-738-4443.

Storage

Store at 68°F to 77°F in controlled room temperature. Keep this medicine out of reach of children & pets. Store in a childproof container. Store this medicine in a cool, dry place at room temperature. Store away from heat and direct sunlight. Do not store this medicine in the bathroom, near the kitchen sink or in damp places. The medicine may break down if exposed to heat or moisture.

Sourced directly from the manufacturer or their approved distributor. Guaranteed genuine product backed by the manufacturer.

Description
Product
Palladia® Tablets
Product Information
Palladia® Tablets are used for the treatment of Patnaik grade II or III, recurrent, cutaneous mast cell tumors (MCTs) with or without regional lymph node involvement in dogs.
For
Dogs
Generic Name
Toceranib
Brand Names
Palladia®
Drug Class
Tyrosine Kinase Inhibitor Antineoplastic
Manufacturer
Zoetis
Product Description & Form
Palladia® 10 mg 30 ct: 7mm, blue, round tablet, not scored, imprinted with TKI;10;Pfizer. (NDC 54771-1690-1)
Palladia® 15 mg 30 ct: 8mm, orange, round tablet, not scored, imprinted with TKI;15;Pfizer. (NDC 54771-1691-1)
Palladia® 50 mg 30 ct: 12mm, red, round tablet, not scored, imprinted with TKI;50;Pfizer. (NDC 54771-1692-1)
Benefits
- FDA-approved medication for grades II or III canine mast cell tumors in dogs
- Works by cutting off blood supply to the tumor and killing tumor cells
Active Ingredients
Toceranib phosphate
Usage
Palladia® should be given orally as directed by your veterinarian. Give dose immediately after removing from the bottle. May be given with or without food. May be hidden in treats, be certain your dog swallows the entire tablet(s). Do not crush or split tablets, it will disrupt the protective film coating. Wear gloves when handling medication and wash hands thoroughly with soap and water after handling.
Stop Palladia® immediately and contact your veterinarian if you notice any of the following changes in your dog: refusal to eat, vomiting or watery stools (especially if more frequent than twice in 24 hours), black tarry stools, bright red blood in vomit or stool, unexplained bruising or bleeding, or if your dog experiences other changes that concern you.
Missed Doses
Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give 2 doses at once.
Side Effects
Side effects may include diarrhea, anorexia, lethargy, vomiting, lameness, weight loss, blood in stool, GI bleeding, dehydration, and itchiness. If these effects continue and become troublesome, contact your veterinarian. Other side effects may occur. If you notice anything unusual, contact your veterinarian.
The presence of systemic mast cell tumor prior to treatment may predispose a dog to clinically significant mast cell degranulation with possible severe systemic adverse reactions when treated with Palladia®. Attempts should be made to rule out systemic mastocytosis prior to initiation of treatment with Palladia®.
Drug & Food Interactions
The following lists examples of medicines that can potentially interact with Palladia®: calcitriol, doxorubicin, fluconazole, itraconazole, lomustine, ketoconazole, NSAIDs, and vinblastine. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.
Make sure to tell your veterinarian what other medication you are giving to your pet. Quite often your veterinarian may prescribe two different medications, and a drug interaction may be anticipated. In this case, your veterinarian may vary the dose and/or monitor your pet more closely.
Cautions
Palladia® is for use in dogs only. Do not use in dogs used for breeding, or for pregnant or lactating. Children should not come in contact with Palladia®. Keep children away from feces, urine, or vomit of treated dogs.
To avoid exposure to drug, wash hands with soap and water after administering Palladia® and wear protective gloves to prevent direct contact with feces, urine, vomit, and broken or moistened Palladia® tablets. Place all waste materials in a plastic bag and seal before
general disposal. Do not wash any items soiled with stool, urine, or vomit from your dog with regular laundry. If eyes are accidentally exposed to the drug, rinse eyes with water immediately. In case of accidental ingestion by a person, seek medical advice immediately, show the package insert or label to the physician. Gastrointestinal discomfort such as vomiting or diarrhea may occur if this drug is accidentally ingested.
Pregnant women, women who may become pregnant, or nursing mothers should pay special attention to these handling precautions. Palladia®, like other drugs in its class, prevents the formation of new blood vessels in tumors. In a similar manner, Palladia® may affect blood vessel formation in the developing fetus and may harm an unborn baby (cause birth defects). For pregnant women, accidental ingestion of Palladia® may have adverse effects on pregnancy.
Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies. If your pet displays symptoms of an allergic reaction, call your veterinarian immediately or go to a veterinary emergency clinic. Symptoms may include but are not limited to: swollen lips, tongue, face, airways; difficulty breathing; agitation; profuse salivation; widespread hives and itching.
Adverse Reactions
If you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer Zoetis at 888-963-8471 or Vetsource customer service at 877-738-4443.
Storage
Store at 68°F to 77°F in controlled room temperature. Keep this medicine out of reach of children & pets. Store in a childproof container. Store this medicine in a cool, dry place at room temperature. Store away from heat and direct sunlight. Do not store this medicine in the bathroom, near the kitchen sink or in damp places. The medicine may break down if exposed to heat or moisture.
Sourced directly from the manufacturer or their approved distributor. Guaranteed genuine product backed by the manufacturer.
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