Potassium Citrate ER Tablets

Potassium citrate is a urinary alkalinizing agent used to prevent the formation of calcium oxalate uroliths (a type of bladder and kidney stones) in animals. It may also be used to supplement low potassium levels in the blood and to decrease acid buildup in the blood and urine. This product is an extended-release (ER) tablet formulation.

*Please note: This is a generic medication. Product packaging and appearance, including size, color, and shape, may differ from the description or images provided and are subject to manufacturer availability.

Dogs and Cats

Potassium citrate

Urocit-K

Urinary alkalinizing agent

Potassium Citrate extended-release tablets may be available in multiple strengths and/or sizes. Please ensure the selected product and package size are appropriate for your pet, as recommended by your veterinarian.

For current availability, please refer to the product selection above.

Potassium Citrate ER Tablets should be given orally as directed by your veterinarian. Please consult your veterinarian before making any changes or discontinuing the prescribed dosing schedule.

This medication should be given with food. Ensure your pet always has access to fresh, clean drinking water while taking this medication.

These tablets should be swallowed whole; do not cut, split, or crush extended-release tablets unless specifically instructed to do so by your veterinarian.

Do not allow your pet to chew or suck on the tablet.

Administer the dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not give two doses at once.

Store in a cool, dry place at a controlled room temperature (68 to 77°F, brief excursions permitted between 59 and 86°F). Keep in a tight, light-resistant container and out of the reach of children and pets. Store away from heat and direct sunlight. Do not store in the bathroom, near the kitchen sink, or in damp places. The medicine may break down if exposed to heat or moisture.

This medication is generally well tolerated, and side effects are considered uncommon. The most common side effect of this medication is GI distress (e.g., nausea, vomiting, diarrhea).

Solid forms of potassium citrate, including these extended-release tablets, may cause esophageal or GI obstruction, ulceration, or perforation. This risk may be increased in animals with preexisting GI conditions. Please discuss your pet’s treatment options with your veterinarian if your pet has difficulty swallowing this medication.

Contact your veterinarian immediately if your pet experiences severe vomiting, extremely low energy levels, muscle weakness, or collapse.

Notify your veterinarian if your pet experiences any of the effects described above, or if you notice any other side effects that are persistent or troublesome.

If you notice anything unusual, please consult your veterinarian.

Your veterinarian will schedule follow-up appointments and blood work to monitor your pet while they are taking this medication. Do not miss any of these follow-ups.

Do NOT administer this medication to animals with hyperkalemia (high potassium levels) or any condition that may increase risk of hyperkalemia (e.g., Addison’s disease, uncontrolled diabetes); aluminum toxicity; severe heart damage and/or failure; GI ulceration or serious GI tract conditions; severe kidney impairment/disease; or a urinary tract infection (UTI) associated with bladder stones.

Use with caution in animals with heart failure, chronic kidney disease, liver impairment, or chronic diarrhea.

Safe use of this medication has not been fully established in breeding, pregnant, or lactating animals. Discuss the risks of using this medication with your veterinarian if your pet is in one of these groups.

Do not administer to animals with a known history or suspected allergy/hypersensitivity to this medication or any of its ingredients. Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies.

If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways; difficulty breathing; agitation; profuse salivation; and widespread hives or itching.

The following drugs* may have potential interactions with this medication: ACE inhibitors (e.g., benazepril, enalapril), aluminum hydroxide, antacids (containing aluminum or bicarbonate), antihistamines (e.g., diphenhydramine, hydroxyzine), ARBs (e.g., telmisartan), aspirin, atropine, digoxin, fluoroquinolone antibiotics (e.g., ciprofloxacin), NSAIDs, opioids, phenobarbital, phenylpropanolamine (Proin), potassium supplements, potassium-sparing diuretics (e.g., spironolactone), tramadol, tetracyclines (e.g., doxycycline, minocycline), and tricyclic antidepressants (e.g., amitriptyline, clomipramine).

*NOTE: this may not be a comprehensive list. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.

Please ensure your veterinarian is aware of all medications and supplements that your pet is currently receiving. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.

If you are concerned that your pet has experienced an adverse reaction to this medication, please contact Vetsource Pet Owner Care at 877-738-4443.

If you have any reason to suspect an overdose, call your doctor/veterinarian or the appropriate poison control resource immediately.

For humans:

The national toll-free Poison Help line, 1-800-222-1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories.

For animals:

The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888-426-4435.

Pet Poison Helpline® also provides a 24/7 animal poison control service at 855-764-7661.

All content, including the images and product description above, is intended for general informational purposes only and should not be considered a substitute for professional veterinary consultation, diagnosis, or treatment.

Consult your veterinarian for complete information about this product and how it fits into your pet's individual treatment plan.