Spironolactone Tablets

Spironolactone Tablets

Spironolactone is an aldosterone antagonist used as a potassium-sparing diuretic. It is used to help reduce the amount of water in the pet’s body by increasing the flow of urine. Spironolactone may be used for several cardiovascular and renal conditions.

Dogs, Cats

Spironolactone

Aldactone®

Aldosterone Antagonist

Spironolactone tablets are mint- or peppermint-flavored.

Spironolactone

Spironolactone should be given orally as directed by your veterinarian. Wash hands after handling this medication.

Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not give two doses at once.

Common side effects may include (but are not limited to): decreased appetite, vomiting, diarrhea, dehydration/excessive thirst, drowsiness, weakness, and diminished urination in relation to fluid intake. Notify your veterinarian if side effects appear and remain troublesome.

In rare cases, facial dermatitis has occurred in cats on this medication. If this is observed, contact your veterinarian.

Other side effects may occur. If you notice anything unusual, contact your veterinarian.

The following medications have been noted to have potential interactions with spironolactone (but may not be a comprehensive list): ACE inhibitors (e.g., enalapril, benazepril), Angiotensin receptor blockers (e.g., telmisartan), beta blockers, desoxycorticosterone pivalate, digoxin, NSAIDs, potassium supplements, and salicylates (e.g., aspirin). Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.

Ensure your veterinarian is aware of all medications and/or supplements you are giving to your pet. Quite often your veterinarian may prescribe two different medications, even if a potential drug interaction may occur. In this case, your veterinarian may vary the dose and/or monitor your pet more closely.

While this medication does not have an FDA-approved indication for animal use, it is a common and acceptable practice for veterinarians to prescribe this human medication for use in animals.

Do not use in pets with high potassium levels, Addison’s disease, acute kidney injury, or significant renal impairment.

Use with caution in pets with history of renal or liver impairment.

Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies.

If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways, difficulty breathing, agitation, profuse salivation, and widespread hives or itching.

This medication may present a hazard to males or females who are actively trying to conceive, women who are pregnant or may become pregnant, and women who are breast feeding, because it may be present in breast milk. Unopened, intact tablets and capsules may not pose the same degree of risk as injectable drugs that usually require extensive preparation. Cutting, crushing, or otherwise manipulating tablets and capsules will increase the risk of exposure. Wear gloves while handling this medication. Wash your hands thoroughly with soap and water after handling this medication.

If you are concerned that your pet has experienced an adverse reaction to this medication, please contact Vetsource customer service at 877-738-4443.

Store in a cool, dry place at a controlled room temperature below 77°F. Keep the medication in a childproof container and out of the reach of children and pets. Store away from heat and direct sunlight. Do not store this medication in the bathroom, near the kitchen sink, or in damp places. The medicine may break down if exposed to heat or moisture.