Product details
Lactulose is a synthetic sugar that is used as an osmotic laxative and ammonia detoxicant in animals.
This product is an oral solution.
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Used to help soften the stool and manage constipation in dogs and cats.
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Can also be used to reduce ammonia blood concentrations in animals with certain conditions (e.g., hepatic encephalopathy).
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Do not use in animals with current intestinal obstruction (blockage). Use with caution in animals with diabetes or preexisting fluid/electrolyte imbalances.
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May be prescribed for other animal species; please consult your veterinarian.
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While this drug does not have an FDA-approved indication for all animal uses, it is commonly accepted for veterinarians to prescribe this medication for use in animals.
*Please note: This is a generic medication. Product packaging and appearance, including size, color, and shape, may differ from the description or images provided and are subject to manufacturer availability.
Product sourced directly from the manufacturer or their approved distributor. Guaranteed genuine product backed by the manufacturer.
For
Dogs and Cats
Active ingredient(s)
Lactulose
Common brand names
Enulose, Cephulac, Generlac
Drug class
Osmotic laxative
Product strength & size
This product contains 10 grams of lactulose per 15 mL of oral solution. Please ensure the selected product and package size are appropriate for your pet, as recommended by your veterinarian.
For current availability, please refer to the product selection above.
Usage
Lactulose Solution should be given orally as directed by your veterinarian. Wash your hands thoroughly with soap and water after handling. Please consult your veterinarian before making any changes or discontinuing the prescribed dosing schedule.
Ensure your pet always has access to fresh, clean drinking water while taking this medication.
Missed doses
Administer the dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not give more medication than prescribed or two doses at once.
Storage
Store in a cool, dry place at a controlled room temperature (68 to 77°F, brief excursions permitted between 59 and 86°F), or as otherwise indicated by the manufacturer product label. Do not freeze.
Keep in a tight, light-resistant container and out of the reach of children and pets. Store away from heat and direct sunlight. Do not store in the bathroom, near the kitchen sink, or in damp places. The medicine may break down if exposed to heat or moisture.
The solution may darken slightly under normal storage conditions; this does not affect the therapeutic efficacy of the medication. Do NOT use if the solution appears extremely dark or turbid (contains visible particles). These are signs that the solution has been contaminated or stored improperly and is no longer fit for use.
Side effects
This medication is generally well tolerated. Possible side effects include (but may not be limited to) gassiness, diarrhea, abdominal pain, bloating, or cramping. These effects usually occur at the start of treatment and improve over time.
Contact your veterinarian immediately if your pet has severe/ongoing diarrhea or shows any signs of dehydration (e.g., dry nose/mouth, appetite loss, decreased energy level, sunken eyes, panting).
Notify your veterinarian if your pet experiences any of the effects described above, or if you notice any other side effects that are persistent or troublesome.
If you notice anything unusual, please consult your veterinarian.
Precautions
Do NOT use in animals with current intestinal obstruction (blockage).
Use with caution in animals with diabetes, as this medication may alter blood sugar levels and/or insulin requirements.
Use with caution in animals that are prone to dehydration or those with preexisting fluid/electrolyte imbalances.
Safe use of this medication has not been established in breeding, pregnant, or lactating animals. Discuss the risks of using this medication with your veterinarian if your pet is in one of these groups.
Do not administer to animals with a known history or suspected allergy/hypersensitivity to this medication or any of its ingredients. Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies.
If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways; difficulty breathing; agitation; profuse salivation; and widespread hives or itching.
Drug and food interactions
The following drugs* may have potential interactions with this medication: acepromazine, antacids (containing aluminum, calcium, and/or magnesium), oral antibiotics, antidiabetic agents (including insulins), antidiarrheals (e.g., kaolin/pectin), azole antifungals (e.g., ketoconazole), corticosteroids (e.g., dexamethasone, prednisone), diuretics (e.g., furosemide, hydrochlorothiazide), fluoroquinolone antibiotics (e.g., ciprofloxacin), hydroxyzine, other laxatives (e.g., polyethylene glycol 3350, psyllium), sotalol, SSRIs (e.g., fluoxetine, sertraline), and warfarin.
*NOTE: this may not be a comprehensive list. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.
Please ensure your veterinarian is aware of all medications and supplements that your pet is currently receiving. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.
Adverse reactions
If you are concerned that your pet has experienced an adverse reaction to this medication, please contact Vetsource Pet Owner Care at 877-738-4443.
Overdose
If you have any reason to suspect an overdose, call your doctor/veterinarian or the appropriate poison control resource immediately.
For humans:
The national toll-free Poison Help line, 1-800-222-1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories.
For animals:
The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888-426-4435.
Pet Poison Helpline® also provides a 24/7 animal poison control service at 855-764-7661.
*Please note: this information is for third-party services and is provided for convenience in case of potential poison-related emergencies. There may be consultation fee for these services.
Disclaimer
The content provided on this page is NOT medical advice.
All content, including the images and product description above, is intended for general informational purposes only and should not be considered a substitute for professional veterinary consultation, diagnosis, or treatment.
Consult your veterinarian for complete information about this product and how it fits into your pet's individual treatment plan.
Last revised: 7/02/2025